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"El Doctor Víctor Hernández Mendible ha escrito una obra excelente sobre la Convención Americana sobre Derechos Humanos en su cincuentenario. Tan brillante aportación nos recuerda que, desde 1969 hasta hoy, el idealismo convencional ha inspirado admirables evoluciones de los ordenamientos de muchos países. Los avances derivados de la convencionalidad han servido para mejorar las garantías y realizar el principio pro homine, de profunda raíz humanista. Un Derecho administrativo sometido al control de convencionalidad es, por muchas razones, mejor que aquel sólo sujeto a los tests de constitucionalidad. Al fin, las normas fundamentales mantienen una impronta nacional, marcados por sesgos históricos y desequilibrios. El enfoque externo y universal en materia de derechos humanos es una salvaguarda de su mejor versión, la incontaminada por los intereses locales". Ricardo Rivero Ortega. Rector de la Universidad de Salamanca. Catedrático de Derecho Administrativo.
Following the mass arrival of European immigrants to Argentina in the early years of the twentieth century new forms of entertainment emerged including tango, films, radio and theater. While these forms of culture promoted ethnic integration they also produced a new kind of polarization that helped Juan Peron to build the mass movement that propelled him to power.
The growth of institutional capacity in the developing world has become a central theme in twenty-first-century social science. Many studies have shown that public institutions are an important determinant of long-run rates of economic growth. This book argues that to understand the difficulties and pitfalls of state building in the contemporary world, it is necessary to analyze previous efforts to create institutional capacity in conflictive contexts. It provides a comprehensive analysis of the process of state and nation building in Latin America and Spain from independence to the 1930s. The book examines how Latin American countries and Spain tried to build modern and efficient state institutions for more than a century - without much success. The Spanish and Latin American experience of the nineteenth century was arguably the first regional stage on which the organizational and political dilemmas that still haunt states were faced. This book provides an unprecedented perspective on the development and contemporary outcome of those state and nation-building projects.
"All over the world, in all democratic States, independently of having a legal system based on the common law or on the civil law principles, the courts – special constitutional courts, supreme courts or ordinary courts – have the power to decide and declare the unconstitutionality of legislation or of other State acts when a particular statute violates the text of the Constitution or of its constitutional principles. This power of the courts is the consequence of the consolidation in contem-porary constitutionalism of three fundamental principles of law: first, the existence of a written or unwritten constitution or of a fundamental law, conceived as a superior law with clear supremacy ...
The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs. These cells are distributed systemically, resulting in general immunosuppression. They also infiltrate tumours, promoting their progression and metastasis by inhibiting the natural anti-tumour immune response. As these cells also interact with classical anti-neoplastic treatments, they have become major therapeutic targets in the pharmaceutical industry and in oncology research.