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The olivo-cerebellar system
  • Language: en
  • Pages: 324

The olivo-cerebellar system

During the last decades, investigations on the olivo-cerebellar system have attained a high level of sophistication, which led to redefinitions of several structural and functional properties of neurons, synapses, connections and circuits. Research has expanded and deepened in so many directions and so many theories and models have been proposed that an ensemble review of the matter is now needed. Yet, hot topics remain open and scientific discussion is very lively at several fronts. One major question, here as well as in other major brain circuits, is how single neurons and synaptic properties emerge at the network level and contribute to behavioural regulation via neuronal plasticity. Othe...

Cortical Development
  • Language: en
  • Pages: 283

Cortical Development

This book reviews recent progress in cortical development research, focusing on the mechanisms of neural stem cell regulation, neuronal diversity and connectivity formation, and neocortical organization. Development of the cerebral cortex, the center for higher brain functions such as cognition, memory, and decision making, is one of the major targets of current research. The cerebral cortex is divided into many areas, including motor, sensory, and visual cortices, each of which consists of six layers containing a variety of neurons with different activities and connections. As this book explains, such diversity in neuronal types and connections is generated at various levels. First, neural stem cells change their competency over time, giving sequential rise to distinct types of neurons and glial cells: initially deep layer neurons, then superficial layer neurons, and lastly astrocytes. The activities and connections of neurons are further modulated via interactions with other brain regions, such as the thalamocortical circuit, and via input from the environment. This book on cortical development is essential reading for students, postdocs, and neurobiologists.

Fisheries Review
  • Language: en
  • Pages: 718

Fisheries Review

  • Type: Book
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  • Published: 1991
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  • Publisher: Unknown

None

NMDA Receptor Protocols
  • Language: en
  • Pages: 201

NMDA Receptor Protocols

Min Li and a panel of hands-on experimentalists detail state-of-the-art molecular techniques for studying NMDA ligand-gated ion channels and developing assays for nontherapeutic lead selection. The topics range from cDNA cloning to in vitro and in vivo investigation of the channel complex in the mammalian brain. Additional topics include the biochemical analysis of the channel protein and the construction of various heterologous systems for both basic research and high throughput screens (HTS) for pharmaceutical chemicals. Although the focus is on NMDA receptors, the methods are applicable to other ligand-gated ion channels and with some modification may be extended to related membrane signaling receptors. NMDA Receptor Protocols offers today's scientists powerful methods for basic research on NMDA receptor structure and function, as well as enormous opportunities for clinical investigation toward the development of novel bioactive compounds.

The History of Neuroscience in Autobiography Volume 6
  • Language: en
  • Pages: 589

The History of Neuroscience in Autobiography Volume 6

The sixth volume of The History of Neuroscience in Autobiography is a collection of autobiographical essays by notable senior scientists who discuss the major events that shaped their discoveries and their influences, as well as the people who inspired them and helped shape their careers as neuroscientists. Each entry also includes a complete CV so that the interested reader may see their rise through the ranks as they achieved some of the highest honors in neuroscience.

Sport Fishery Abstracts
  • Language: en
  • Pages: 708

Sport Fishery Abstracts

  • Type: Book
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  • Published: 1991
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  • Publisher: Unknown

None

Molecular Biology of the Human Brain
  • Language: en
  • Pages: 224

Molecular Biology of the Human Brain

  • Type: Book
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  • Published: 1982
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  • Publisher: Unknown

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Protein Engineering
  • Language: en
  • Pages: 441

Protein Engineering

  • Type: Book
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  • Published: 2012-12-02
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  • Publisher: Elsevier

Protein Engineering: Applications in Science, Medicine, and Industry deals with the scientific, medical, and industrial applications of protein engineering. Topics range from protein structure and design to mutant analysis and complex systems. Applications such as production of novel antibiotics, genetic transformation of plants, and genetic engineering of bioinsecticides are described. This book is comprised of 25 chapters and begins with an overview of trends and developments in protein chemistry and their relevance to protein engineering, followed by a discussion on protein sequence data banks. Subsequent chapters explore the design and construction of biologically active peptides, includ...

Index of Patents Issued from the United States Patent Office
  • Language: en
  • Pages: 2456

Index of Patents Issued from the United States Patent Office

  • Type: Book
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  • Published: 1978
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  • Publisher: Unknown

None

Neuroscience Letters
  • Language: en
  • Pages: 516

Neuroscience Letters

  • Type: Book
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  • Published: 1996
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  • Publisher: Unknown

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