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Among the most important innovations in the history of life is the transition from single-celled organisms to more complex, multicellular organisms. Multicellularity has evolved repeatedly across the tree of life, resulting in the evolution of new kinds of organisms that collectively constitute a significant portion of Earth’s biodiversity and have transformed the biosphere. This volume examines the origins and subsequent evolution of multicellularity, reviewing the types of multicellular groups that exist, their evolutionary relationships, the processes that led to their evolution, and the conceptual frameworks in which their evolution is understood. This important volume is intended to serve as a jumping-off point, stimulating further research by summarizing the topics that students and researchers of the evolution of multicellularity should be familiar with, and highlighting future research directions for the field. Chapter 13 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.
Argues that systems approaches are necessary in order to identify and understand important features of the world.
A proposal for a new model of the evolution of gene regulation networks and development that draws on work from artificial intelligence and philosophy of mind. Each of us is a collection of more than ten trillion cells, busy performing tasks crucial to our continued existence. Gene regulation networks, consisting of a subset of genes called transcription factors, control cellular activity, producing the right gene activities for the many situations that the multiplicity of cells in our bodies face. Genes working together make up a truly ingenious system. In this book, Roger Sansom investigates how gene regulation works and how such a refined but simple system evolved. Sansom describes in det...
Humans are primates, and our closest relatives are the other African apes - chimpanzees closest of all. With the mapping of the human genome, and that of the chimp, a direct comparison of the differences between the two, letter by letter along the billions of As, Gs, Cs, and Ts of the DNA code, has led to the widely vaunted claim that we differ from chimps by a mere 1.6% of our genetic code. A mere hair's breadth genetically! To a rather older tradition of anthropomorphizing chimps, trying to get them to speak, dressing them up for 'tea parties', was added the stamp of genetic confirmation. It also began an international race to find that handful of genes that make up the difference - the ge...
What does it mean to say that mutation is random? How does mutation influence evolution? Are mutations merely the raw material for selection to shape adaptations? The author draws on a detailed knowledge of mutational mechanisms to argue that the randomness doctrine is best understood, not as a fact-based conclusion, but as the premise of a neo-Darwinian research program focused on selection. The successes of this research program created a blind spot - in mathematical models and verbal theories of causation - that has stymied efforts to re-think the role of variation. However, recent theoretical and empirical work shows that mutational biases can and do influence the course of evolution, in...
Wer haftet, wenn sich selbst ausbreitende Gentechnik grenzüberschreitende Schäden verursacht? Mit Gene Drives und ähnlichen Verfahren wird es bald möglich sein, das Erbgut wild lebender Arten, Keime und Nutzpflanzen direkt in der Umwelt zu verändern. Dies könnte helfen, drängende Probleme in der öffentlichen Gesundheit, im Naturschutz und in der Ernährungssicherheit zu lösen. Allerdings bergen diese Verfahren auch das Risiko einer unkontrollierten Ausbreitung über Staatsgrenzen hinweg. Anhand einer grundlegenden Untersuchung der einschlägigen Verträge und des Völkergewohnheitsrechts zu Prävention und Haftung für grenzüberschreitende Schäden wird aufgezeigt, dass das derzeit geltende Völkerrecht dieser Herausforderung noch nicht gewachsen ist.
We are entering a particularly fruitful period in evolutionary genetics, as rapid technological progress transforms the investigation of genetic variation within and between species. Molecular Methods for Evolutionary Genetics is a collection of advanced molecular biology protocols and general overviews intended to represent the essential methods currently bringing evolutionary genetics to fruition. Divided into six thematic sections, this volume covers methods for characterizing genomes, diverse approaches to enrich DNA for subsets of the genome prior to sequencing, and state-of-the-art protocols for sampling genetic variation for genetic mapping studies and population genetic studies (RAD ...
The Routledge Handbook of the Ethics of Human Enhancement provides readers with a philosophically rich and scientifically grounded analysis of human enhancement and its ethical implications. A landmark in the academic literature, the volume covers human enhancement in genetic engineering, neuroscience, synthetic biology, regenerative medicine, bioengineering, and many other fields. The Handbook includes a diverse and multifaceted collection of 30 chapters—all appearing here in print for the first time— that reveal the fundamental ethical challenges related to human enhancement. The chapters have been written by internationally recognized leaders in the field and are organized into seven ...
This book presents the proceedings of the 1st International Symposium on Intelligent and Distributed Computing, IDC 2007, held in Craiova, Romania, October 2007. Coverage includes: autonomous and adaptive computing; data mining and knowledge discovery; distributed problem solving and decision making; e-business, e-health and e-learning; genetic algorithms; image processing; information retrieval; intelligence in mobile and ubiquitous computing.
The association between our ancestors and fire, somewhere around six to four million years ago, had a tremendous impact on human evolution, transforming our earliest human ancestor, a being communicating without speech but with insight, reason, manual dexterity, highly developed social organization, and the capability of experimenting with this new technology. As it first associated with and then began to tame fire, this extraordinary being began to distance itself from its primate relatives, taking a path that would alter its environment, physiology, and self-image. Based on her extensive research with nonhuman primates, anthropologist Frances Burton details the stages of the conquest of fire and the systems it affected. Her study examines the natural occurrence of fire and describes the effects light has on human physiology. She constructs possible variations of our earliest human ancestor and its way of life, utilizing archaeological and anthropological evidence of the earliest human-controlled fires to explore the profound physical and biological impacts fire had on human evolution.