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Applied Predictive Modeling
Applied Predictive Modeling covers the overall predictive modeling process, beginning with the crucial steps of data preprocessing, data splitting and foundations of model tuning. The text then provides intuitive explanations of numerous common and modern regression and classification techniques, always with an emphasis on illustrating and solving real data problems. The text illustrates all parts of the modeling process through many hands-on, real-life examples, and every chapter contains extensive R code for each step of the process. This multi-purpose text can be used as an introduction to predictive models and the overall modeling process, a practitioner’s reference handbook, or as a t...
Feature Engineering and Selection
The process of developing predictive models includes many stages. Most resources focus on the modeling algorithms but neglect other critical aspects of the modeling process. This book describes techniques for finding the best representations of predictors for modeling and for nding the best subset of predictors for improving model performance. A variety of example data sets are used to illustrate the techniques along with R programs for reproducing the results.
Tidy Modeling with R
Get going with tidymodels, a collection of R packages for modeling and machine learning. Whether you're just starting out or have years of experience with modeling, this practical introduction shows data analysts, business analysts, and data scientists how the tidymodels framework offers a consistent, flexible approach for your work. RStudio engineers Max Kuhn and Julia Silge demonstrate ways to create models by focusing on an R dialect called the tidyverse. Software that adopts tidyverse principles shares both a high-level design philosophy and low-level grammar and data structures, so learning one piece of the ecosystem makes it easier to learn the next. You'll understand why the tidymodels framework has been built to be used by a broad range of people. With this book, you will: Learn the steps necessary to build a model from beginning to end Understand how to use different modeling and feature engineering approaches fluently Examine the options for avoiding common pitfalls of modeling, such as overfitting Learn practical methods to prepare your data for modeling Tune models for optimal performance Use good statistical practices to compare, evaluate, and choose among models
Nonclinical Statistics for Pharmaceutical and Biotechnology Industries
This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods important to the nonclinical science areas within the pharmaceutical and biotechnology industries. Specifically the Discovery and Translational sciences, the Safety/Toxiology sciences, and the Chemistry, Manufacturing and Controls sciences. Drug discovery and development is a long and costly process. Most decisions in the drug development process are made with incomplete information. The data is rife with uncertainties and hence risky by nature. This is therefore the purview of Statistics. As such, this book aims to introduce readers to important statistical thinking and its application in these nonclinical areas. The chapters provide as appropriate, a scientific background to the topic, relevant regulatory guidance, current statistical practice, and further research directions.
Black-Body Theory and the Quantum Discontinuity, 1894-1912
"A masterly assessment of the way the idea of quanta of radiation became part of 20th-century physics. . . . The book not only deals with a topic of importance and interest to all scientists, but is also a polished literary work, described (accurately) by one of its original reviewers as a scientific detective story."—John Gribbin, New Scientist "Every scientist should have this book."—Paul Davies, New Scientist
Interactive Composition
Manzo and Kuhn provide readers with all the practical skills and insights necessary to compose and perform electronic music in a variety of popular styles. Even those with little experience with digital audio software will learn to design powerful systems that facilitate their own compositional ideas.
Hands-On Machine Learning with R
Hands-on Machine Learning with R provides a practical and applied approach to learning and developing intuition into today’s most popular machine learning methods. This book serves as a practitioner’s guide to the machine learning process and is meant to help the reader learn to apply the machine learning stack within R, which includes using various R packages such as glmnet, h2o, ranger, xgboost, keras, and others to effectively model and gain insight from their data. The book favors a hands-on approach, providing an intuitive understanding of machine learning concepts through concrete examples and just a little bit of theory. Throughout this book, the reader will be exposed to the enti...
Expert Indexing in Oracle Database 11g
Expert Indexing in Oracle Database 11g is about the one database structure at the heart of almost all performance concerns: the index. Database system performance is one of the top concerns in information technology today. Administrators struggle to keep up with the explosion of access and activity driven by the proliferation of computing into everything from phones to tablets to PCs in our increasingly connected world. At the heart of any good-performing database lies a sound indexing strategy that makes appropriate use of indexing, and especially of the vendor-specific indexing features on offer. Few databases fully exploit the wealth of data access mechanisms provided by Oracle. Expert In...
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Shifting Paradigms
The publication of Thomas S. Kuhn's "Structure of Scientific Revolutions" in 1962 stands for a turning point in the history and philosophy of science. The repercussions of this work have rearticulated the theoretical framework of history and philosophy of science and have also generated discussions that contributed to the formation of the communities of historians as well as philosophers of science in many parts of the world. Different approaches to history of science have since emerged and most of them have the "Structure" as their reference point. In October 2012, a conference at the Max Planck Institute for the History of Science brought together some of the historians of science whose wo...
