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This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.
This book presents recent advances and developments in control, automation, robotics, and measuring techniques. It presents contributions of top experts in the fields, focused on both theory and industrial practice. In particular the book is devoted to new ideas, challenges, solutions and applications of Mechatronics. The particular chapters present a deep analysis of a specific technical problem which is in general followed by a numerical analysis and simulation, and results of an implementation for the solution of a real world problem. The presented theoretical results, practical solutions and guidelines will be useful for both researchers working in the area of engineering sciences and for practitioners solving industrial problems.
Separation distinction between the roles of the producer and consumer has become blurred with the development of new science and technologies enabling the emergence of the prosumer, or the active consumer. In the IT sector, the role of the end-user has broadened to include innovation and development practices in addition to the traditional consumer activities. As such, businesses must create opportunities for product development and innovation by the consumers. Frameworks of IT Prosumption for Business Development investigates the latest empirical research on active use of information technology resources, enabling users with new methodologies, tools, and opportunities to impact application development processes. The objective of this reference book is to mobilize end-users to take a more active role in their own IT solutions, which will in turn assist in the development of best practices in IT at all levels.
Thinking in terms of facts and rules is perhaps one of the most common ways of approaching problem de?nition and problem solving both in everyday life and under more formal circumstances. The best known set of rules, the Ten Commandments have been accompanying us since the times of Moses; the Decalogue proved to be simple but powerful, concise and universal. It is logically consistent and complete. There are also many other attempts to impose rule-based regulations in almost all areas of life, including professional work, education, medical services, taxes, etc. Some most typical examples may include various codes (e.g. legal or tra?c code), regulations (especially military ones), and many systems of customary or informal rules. The universal nature of rule-based formulation of behavior or inference principles follows from the concept of rules being a simple and intuitive yet powerful concept of very high expressive power. Moreover, rules as such encode in fact functional aspects of behavior and can be used for modeling numerous phenomena.
This book presents a systematic account on Poles’ attitudes toward ethnic, religious, political, and sexual minorities. It investigates Poland’s reputation as an intolerant, anti-Semitic, and homophobic country. Counter to a simplistic image of Poland as a hotbed of intolerance, the book shows that Polish intolerance has many faces. For one thing, Poles’ attitudes toward diversity vary from one group to another. For another, the extent to which Poles’ attitudes are more or less negative depends on the right or activity they are asked to support and who the respondents happen to be. The book is the most comprehensive and empirically sophisticated synthesis of Poles’ attitudes toward...
Discusses in the practical and theoretical aspects of one-period asset allocation, i.e. market Modeling, invariants estimation, portfolia evaluation, and portfolio optimization in the prexence of estimation risk The book is software based, many of the exercises simulate in Matlab the solution to practical problems and can be downloaded from the book's web-site
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"Uwaga! /// Trzymasz w ręku klucz do świata Starszych Panów. Zawartość /// Pierwszy na świecie przegląd wszystkich dokonań twórców Kabaretu Starszych Panów ze szczególnym uwzględnieniem piosenek. Przestroga! /// Lektura zdradliwa, mogąca przyprawić o zawroty serca, mocniejsze bicie głowy i chorobliwe ataki zdrowego śmiechu. Przed użyciem skonsultuj się z drukarzem. Nigdzie indziej! /// Nie weźmiesz udziału w zabawie rytmicznej dla zdziecinniałych staruszków; nie dowiesz się, jaką dziedzinę wiedzy reprezentuje „pędologia”; nie prześledzisz ewolucji piosenki „Ścieżką pośród łąk”; nie usłyszysz o istnieniu Eldolarado i nie przeczytasz o ogólnokrajowym kryzysie guzikowym. "
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