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Circulating Molecular Biomarkers: Next-Generation Tools for Monitoring Minimal Residual Disease in Cancer Patients
  • Language: en
  • Pages: 137

Circulating Molecular Biomarkers: Next-Generation Tools for Monitoring Minimal Residual Disease in Cancer Patients

Traditional cancer diagnosis relies on tissue biopsy, blood testing as well as medical imaging. By the detection moment, in most cases the tumor size may reach several millimeters and the risk of distant metastasis is unavoidable. Even, following drug treatment, there is no accurate and timely way to follow up the success of treatment. New reliable tumor-specific biomarkers/tools that allow non-invasive early cancer detection as well as monitoring of anti-cancer therapeutic regime is highly demanded. To tackle limitations of traditional cancer management, liquid biopsy has emerged which screen bodily fluids using ultrasensitive biosensing systems capable of simultaneous capturing and studying horizontal gene transfer (HGT) materials including circulating tumor cells (CTCs), exosomes, cell-free DNA, and apoptotic bodies. These are messengers and/or delivery systems by which tumor cells are communicating as well as transforming/sharing new phenotypes with each other resulting in drug resistance, distant metastatic outbreaks, and cancer recurrence. Acting as next-generation prognostic and therapeutic tools call for understanding the molecular mechanisms by which HGT works to tran

Neurodegeneration Nanotechnology in Neurodegenerative Diseases
  • Language: en
  • Pages: 335

Neurodegeneration Nanotechnology in Neurodegenerative Diseases

This book stems from the urgent necessity to address neurodegenerative diseases, which are among the most severe health challenges currently confronting society. Neurodegenerative diseases have become a major threat to public health in recent years, impacting millions of people globally and creating a substantial strain on healthcare systems and society as a whole. Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis are examples of these diseases. This book offers a thorough survey of the latest developments in this rapidly growing field. This book is targeted towards a wide range of readers, including academics, researchers, medical professionals, students, policy makers, and anybody else who is interested in the convergence of neuroscience, nanotechnology, and healthcare. Irrespective of one's familiarity with the subject, this book provides motivation and insightful information to bolster our group's endeavors in combating these debilitating diseases.

Collective Behavior of Magnetic Micro/Nanorobots
  • Language: en
  • Pages: 360

Collective Behavior of Magnetic Micro/Nanorobots

  • Type: Book
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  • Published: 2024-01-26
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  • Publisher: CRC Press

Collective Behavior of Magnetic Micro/Nanorobots: Control, Imaging, and Applications reviews recent advances in the design and construction of magnetic collective micro/nanorobot systems, and promotes the bridging of the gap between their theoretical investigation and practical applications. By summarizing the recent progress in control, imaging, and biomedical applications of collective micro/nanorobots, the authors show the big picture of micro/nanorobotics and the roadmap of collective micro/nanorobots. They then discuss the control, imaging, and biomedical applications of collective micro/nanorobots, respectively, demonstrating the state-of-the-art techniques and ideas for designing systems of collective micro/nanorobots that can help researchers have a better understanding and further stimulate the development of such an exciting field. This book is suitable for scientists, engineers, and students involved in the study of robotics, control, materials, and mechanical/electrical engineering.

Nanozymes
  • Language: en
  • Pages: 422

Nanozymes

  • Type: Book
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  • Published: 2021-11-19
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  • Publisher: CRC Press

This book presents the state-of-the-art advances and applications of nanozymes, the recently developing branch of enzymology that synthesizes and uses nanomaterials that mimic the function of traditional enzymes. During the past decade, the study of nanozymes has grown rapidly. Several new nanomaterials that exhibit enzymatic actions have been identified, along with new applications for their practical use. This book draws upon the work of experts from around the world and provides an in-depth analysis and cutting-edge overview of nanozymes, with an eye toward their present and future applications. Chapters are arranged in a logical order to provide physio-chemical characterization of nanozy...

Microextraction Techniques in Analytical Toxicology
  • Language: en
  • Pages: 268

Microextraction Techniques in Analytical Toxicology

  • Type: Book
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  • Published: 2021-12-31
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  • Publisher: CRC Press

Microextraction Techniques in Analytical Toxicology provides the information readers need to include about cutting-edge sample preparation techniques into their everyday analytical practice, including comprehensive information about principles and state-of-the-art microextraction sample preparation techniques for the analysis of drugs and poisons in biological specimens, especially in forensic and clinical settings. This book also focuses on theoretical discussions of solid-based and liquid-based microextraction techniques, their method development, validation, and applications. A detailed compilation of analytical protocols based on published microextraction procedures to aid in method deve...

Smart Micro- and Nanomaterials for Drug Delivery
  • Language: en
  • Pages: 444

Smart Micro- and Nanomaterials for Drug Delivery

  • Type: Book
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  • Published: 2024-08-27
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  • Publisher: CRC Press

Smart drug delivery at both the micro- and nanoscale is an evolving field with numerous potential applications. It has the potential to revolutionize drug therapy by making treatments more effective, reducing side effects, and improving patient outcomes. This book presents a comprehensive review of the most recent studies on smart micro- and nanomaterials with a focus on their “smart” activity for formation of targeted and responsive drug-delivery carriers. This volume: Introduces readers to the fundamentals of these the micro- and nanoscale materials as well as approaches to smart drug delivery and drug delivery systems. Covers polymers, metals, and composite materials as well as quantu...

Advanced Therapies for Cardiac Regeneration
  • Language: en
  • Pages: 324

Advanced Therapies for Cardiac Regeneration

The Research Topic is organized in the framework of the project BIORECAR (grant number: 772168; http://www.biorecar.polito.it/index.html)

Functional Biomaterials
  • Language: en
  • Pages: 325

Functional Biomaterials

  • Type: Book
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  • Published: 2023-09-22
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  • Publisher: CRC Press

Discusses design chemistry, modification, and processing of biomaterials Describes the efficacy of biomaterials at various scales for biological response and drug delivery Demonstrates technological advances from conventional to additive manufacturing Covers future of biofabrication and customized medical devices

Smart Micro- and Nanomaterials for Pharmaceutical Applications
  • Language: en
  • Pages: 348

Smart Micro- and Nanomaterials for Pharmaceutical Applications

  • Type: Book
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  • Published: 2024-08-27
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  • Publisher: CRC Press

Smart drug delivery refers to a targeted drug delivery or precision drug delivery system that allows drugs to be administered to a specific location in the body or at a specific time with enhanced precision and control. This approach has several advantages, including maximizing the therapeutic effects of a drug while minimizing side effects. This book presents various stimuli-responsive micro- and nanomaterials for pharmaceutical industries. This volume: Covers the global market perspective of micro- and nano-smart materials in pharmaceutical industries. Details various processing routes. Discusses mechanisms for target release. Addresses applications in oral drug delivery, anticancer agents, anti-tumor drug delivery, and drugs for management of infection. This reference work is written to support researchers in the fields of materials engineering and biotechnology with the goal of improving the diagnosis and treatment of disease and patient quality of life.

Present Status and Prospects of Plant Associated Fungi
  • Language: en
  • Pages: 620

Present Status and Prospects of Plant Associated Fungi

This comprehensive book offers a fascinating exploration of the dynamic relationships that exist between plants and fungi, shedding light on the latest advancements in research and opening a window into the remarkable potential of these partnerships. From mycorrhizal networks that enhance plant nutrient uptake to endophytic fungi that fortify plant defences and produce bioactive secondary metabolites of medicinal importance, this book unravels the multifaceted role that fungi play in shaping the health and resilience of plant ecosystems. Whether you're a seasoned mycologist, a curious botanist, or simply intrigued by the wonders of nature's collaborations, this book provides a captivating journey through the diverse realms of plant-fungi interactions, offering a glimpse into the promising prospects that these partnerships hold for the future exploration and application in areas ranging from sustainable agriculture to drug discovery, ecological restoration and beyond.