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Cardiovascular Genomics
  • Language: en
  • Pages: 367

Cardiovascular Genomics

Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both the cutting-edge scientific approaches now possible and the results obtained from them in the new science of cardiovascular genomics.

Principles of Molecular Cardiology
  • Language: en
  • Pages: 604

Principles of Molecular Cardiology

An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.

CT of the Heart
  • Language: en
  • Pages: 391

CT of the Heart

Leading clinicians and researchers from around the world review the full scope of current developments, research, and scientific controversy regarding the principles and applications of cardiac CT. Richly illustrated with numerous black-and-white and color images, the book discusses the interpretation of CT images of the heart in a variety of clinical, physiological, and pathological applications. The authors emphasize current state-of-the-art uses of CT, but also examine developments at the horizon. They also review the technical basis of CT image acquisition, as well as tools for image visualization and analysis.

Atrial Fibrillation
  • Language: en
  • Pages: 452

Atrial Fibrillation

This important new book presents advancements in the treatment and prevention of Atrial Fibrillation (AF). The reader is provided with the latest information that is critically important in the daily care and for the potential cure of patients with AF. Each chapter deals with a different aspect of AF and each chapter is authored by internationally recognized experts in the evolving field of cardiac electrophysiology. This book is a single source that provides a multi-perspective look at and approach to AF. Because AF is so prevalent and affects all areas of medicine, the information in this book will be useful to all those in the medical field.

Nuclear Cardiology, The Basics
  • Language: en
  • Pages: 439

Nuclear Cardiology, The Basics

The purpose of this book is to provide the outline for the "nuts and bolts" establishment and operation of a nuclear cardiology laboratory. In so doing, the authors have attempted to deal with the relevant issues that a laboratory director must address in either setting up the laboratory or maintaining its competitive edge and clinical competence over time. The authors primarily attempted to identify issues related to outpatient imaging facilities. However, where appropriate issues related to inpatients in hospital-based laboratories are also discussed.

Gene Delivery Systems
  • Language: en
  • Pages: 307

Gene Delivery Systems

  • Type: Book
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  • Published: 2022-07-01
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  • Publisher: CRC Press

This unique volume in our Drugs and Pharmaceutical Sciences series covers the development of gene therapy today, the technology involved, clinical applications of siRNA, non-viral vector-based mRNA delivery using nanotechnology, and RNA based vaccines for treating the infectious diseases. It also presents the current application of the CRISPR/Cas9 gene-editing technique which has revolutionized genome editing and which was awarded the 2020 Nobel Prize in Chemistry. Several new drug delivery systems are explored for the applications of gene therapy. These are found to be useful in treating chronic illnesses, including cancer and infectious diseases. Key Features: Overview of the development of gene therapy Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing Presents CRISPR gene therapy recent trends and applications Discusses siRNA, mRNA, and DNA plasmids

Antisense Technology, Part B: Applications
  • Language: en
  • Pages: 683

Antisense Technology, Part B: Applications

  • Type: Book
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  • Published: 1999-11-10
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  • Publisher: Elsevier

Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods which inhibit gene expression permit studies probing the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedically-oriented research. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences.

Essentials of Restenosis
  • Language: en
  • Pages: 468

Essentials of Restenosis

Leading interventional cardiologists, including Patrick Serruys, provide the gold-standard reference on the treatment of restenosis for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field, cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy.

Research Grants
  • Language: en
  • Pages: 584

Research Grants

  • Type: Book
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  • Published: 1988
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  • Publisher: Unknown

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Gene Therapy Methods
  • Language: en
  • Pages: 769

Gene Therapy Methods

  • Type: Book
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  • Published: 2002-03-06
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  • Publisher: Elsevier

This volume in the prestigious Methods in Enzymology series discusses methods currently used in preclinical and clinical gene therapy. Subjects covered in this book, such as the use of adeno-associated virus delivery for treatment of Parkinson's disease, are topical and are presented in the methods-oriented style popularized by this series. Discusses methods currently used in preclinical and clinical gene therapy Covers the use of adeno-associated virus delivery for treatment of Parkinson's disease