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Computational Systems Biology of Pathogen-Host Interactions
A thorough understanding of pathogenic microorganisms and their interactions with host organisms is crucial to prevent infectious threats due to the fact that Pathogen-Host Interactions (PHIs) have critical roles in initiating and sustaining infections. Therefore, the analysis of infection mechanisms through PHIs is indispensable to identify diagnostic biomarkers and next-generation drug targets and then to develop strategic novel solutions against drug-resistance and for personalized therapy. Traditional approaches are limited in capturing mechanisms of infection since they investigate hosts or pathogens individually. On the other hand, the systems biology approach focuses on the whole PHI ...
Exploring Mathematical Modeling in Biology Through Case Studies and Experimental Activities
Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Inc...
Mathematics for Human Flourishing in the Time of COVID-19 and Post COVID-19
The International Chair in Mathematical Physics and Applications (ICMPA - UNESCO chair), University of Abomey-Calavi, Benin, and the Center for Applied Mathematics of the Faculty of Mechanical Engineering Niš, CAM-FMEN, organized a webinar on Mathematics for human flourishing in the time of COVID-19 and post COVID-19, 21 October 2020, supported by the City of Niš. The objectives of the webinar were to give precise information about the work that scientists do to cure the disease, to push forward technology, to understand our society and create new expressions of humanity, and to question the role of mathematics in the responses to this pandemic.
Molecular pathogenesis of pneumococus
Streptococcus pneumoniae (the pneumococcus) is a commensal of the human nasopharynx during childhood, but also causes a variety of infections, such as otitis media (OM), pneumonia, bacteremia, and meningitis, mainly affecting infants, the elderly and immunocompromised patients. Pneumococcal pneumonia alone produces more child deaths, every year, than any other bacterial disease worldwide. To date, more than 90 distinct capsular serotypes have been identified. Current pneumococcal conjugate vaccines (PCV) protect against 7, 10 or 13 different pneumococcal types. These vaccines have decreased the burden of pneumococcal disease produced by vaccine types but provide poor protection against non-v...
Zoonotic Diseases: Their Hosts and Vectors
Topic Editor Rubén Bueno Marí is employed by Lokimica Laboratorios. All other Topic Editors declare no competing interests with regard to the Research Topic subject.
Molecular Pathogenesis of Pneumococcus
Streptococcus pneumoniae has been for decades the number one bacterial killer of children in the world. Although vaccination with pneumococcal vaccines [PCV7, PCV10, and PCV13 (children) or PPSV23 (adults)] has helped decrease the burden of pneumococcal disease (PD), mortality remains high. Therefore, pathogenesis studies are still key toward our understanding of PD and its control. The introduction of pneumococcal vaccines has also created a niche for vaccine-escape clones. Moreover, the rise of multi-drug resistant clones around the world has also posed a serious threat in recent years. The proposed special issue of Frontiers in Cellular and Infection Microbiology highlights many of the recent advances that have been made in pneumococcal pathogenesis, colonization and antibiotic resistance by groups in Latino America, Europe, and the USA.
Modeling, Control and Drug Development for COVID-19 Outbreak Prevention
This book is well-structured book which consists of 31 full chapters. The book chapters' deal with the recent research problems in the areas of modeling, control and drug development, and it presents various techniques of COVID-19 outbreak prevention modeling. The book also concentrates on computational simulations that may help speed up the development of drugs to counter the novel coronavirus responsible for COVID-19. This is an open access book.
