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Since modeling multiscale phenomena in systems biology and neuroscience is a highly interdisciplinary task, the editor of the book invited experts in bio-engineering, chemistry, cardiology, neuroscience, computer science, and applied mathematics, to provide their perspectives. Each chapter is a window into the current state of the art in the areas of research discussed and the book is intended for advanced researchers interested in recent developments in these fields. While multiscale analysis is the major integrating theme of the book, its subtitle does not call for bridging the scales from genes to behavior, but rather stresses the unifying perspective offered by the concepts referred to in the title. It is believed that the interdisciplinary approach adopted here will be beneficial for all the above mentioned fields.
This book describes the critical areas of research and development towards viable integrated solar fuels systems, the current state of the art of these efforts and outlines future research needs.
Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.
Suitable for graduate students in chemical physics, statistical physics, and physical chemistry, this text develops an innovative, probabilistic approach to statistical mechanics. The treatment employs Gauss's principle and incorporates Bose-Einstein and Fermi-Dirac statistics to provide a powerful tool for the statistical analysis of physical phenomena. The treatment begins with an introductory chapter on entropy and probability that covers Boltzmann's principle and thermodynamic probability, among other topics. Succeeding chapters offer a case history of black radiation, examine quantum and classical statistics, and discuss methods of processing information and the origins of the canonical distribution. The text concludes with explorations of statistical equivalence, radiative and material phase transitions, and the kinetic foundations of Gauss's error law. Bibliographic notes complete each chapter.
Modern astronomy has been characterized by an enormous growth in data acquisition - from new technologies in telescopes, detectors, and computation. One can now compile catalogs of tens or hundreds of millions of stars or galaxies and databases from satellite-based observations are reaching terabit proportions. This wealth of data gives rise to statistical challenges not previously encountered in astronomy. This book is the result of a workshop held at Pennsylvania State University in August 1991 that brought together leading astronomers and statisticians to consider statistical challenges encountered in modern astronomical research. The chapters have all been thoroughly revised in the light of the discussions at the conference, and some of the lively discussion is recorded here as well.
How visual content is represented in neuronal population codes and how to analyze such codes with multivariate techniques. Vision is a massively parallel computational process, in which the retinal image is transformed over a sequence of stages so as to emphasize behaviorally relevant information (such as object category and identity) and deemphasize other information (such as viewpoint and lighting). The processes behind vision operate by concurrent computation and message passing among neurons within a visual area and between different areas. The theoretical concept of "population code" encapsulates the idea that visual content is represented at each stage by the pattern of activity across...