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Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy of ionizing radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Triple modality (thermo-chemo-radiotherapy) or other treatment combinations have not been fully evaluated and may demonstrate extended clinical applications in the future. Problems remain with regard to maximizing the effects of hyperthermia as they are influenced by a variety of external and intrinsic factors including bloodflow, microenvironment etc. While the previous volume has summarized more theoretical aspects of hyper thermia, i.e. biology, physiology and physics, the present volume compiles the current knowledge relative to the clinical applications of hyperthermia in combina tion with radiation therapy and/or chemotherapy, providing a comprehensive over view of its use in cancer management.
Recent advances in diagnostic technology, including imaging, gene analysis and histopathology, form one cornerstone of this update for health care specialists treating patients with musculoskeletal cancer. The other cornerstone consists of chemotherapy and radiotherapy, as well as highlights in surgical treatment and rehabilitation. The complete structure conveys a systematic understanding of musculoskeletal oncology, with sections on limb saving procedures, reconstruction methods of bone and soft tissues, tumor prosthesis and spinal reconstruction in metastatic bone tumors. All the information is placed under the encompassing goal of total care for the patient.
Synchrotron radiation has important applications in medical imaging, especially in such areas as intravenous coronary angiography, mammography, bronchography, and monochromatic computed tomography. In medicine, phase contrast imaging is a particularly exciting development, with the potential to become a new X-ray eye in the 21st century. To discuss these and related topics, medical doctors met with physicists and other researchers in Haga, Japan, in August 1997. This volume contains the proceedings of the International Workshop on Medical Applications of Synchrotron Radiation (HAGA 97), where practitioners from the world of medicine could communicate directly with researchers from the world of physics to discuss practical and theoretical aspects of medical imaging with synchrotron radiation. This volume, presenting the outcome of the discussions and presentations in the workshop, is a valuable resource to all who are interested in medical imaging and physics.