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Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondrial dysfunction, proteotoxic insults, genetic inconsistency, etc. are responsible for the dysfunction of the neuronal protein quality control system, targeting protein quality control has become an auspicious approach to halt the propagation of neurodegeneration. Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the role of the protein quality control in neurodegenerative disorders and potential therapeutic strategies to combat the development and propagation of neurodegeneration. Featuring coverage on a broad range of topics such as molecular chaperones, protein misfolding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.
These conference proceedings cover an outstanding view for academics and professionals to share research findings on the latest developments in real estate and construction management. The Chinese Research Institute of Construction Management (CRIOCM) in collaboration with Chongqing University organized CRIOCM2014, the 19th International Symposium on “Advancement of Construction Management and Real Estate.” The proceedings collect 105 selected papers addressing the following key themes: Sustainable Urbanization, Sustainable Construction, Urban Construction and Management, Affordable Housing, Urban Land Development and Utilization, Management for Large Infrastructure Projects, Green Construction Materials and Construction Waste Management, Development and Management for Mountainous Towns, Advancement of Construction Project Management, Redevelopment in Disaster Areas, Law and Policies for Construction and Real Estate, Information Technology for Construction Management and Real Estate and lastly Other Topics.
Value is added to projects through the relationships surrounding the client; the focus of this book is therefore the client as project, rather than the building on the ground. It shows how to create and maintain effective relationships between the client and the project team, as well as intra-coalition relationships Students, academics and practitioners need to understand the changing nature of reforms from successive calls for change by the industry’s various clients and client groups. Project team network relationships are a function of mindsets, behaviour and competencies of individuals and The Management of Complex Projects: a relationship approach: • Explores the relationship at the project interface: client-design team-contractor, stakeholders and supply chain relations • Examines different concepts to the development and management of relationships; formation and maintenance issues • Highlights some of the key issues that require development, both academically and through applied research. Most project management books cover tools and techniques; this one covers the softer skills and shows how crucial good relationships are to the successful management of projects.
Innovation in building design and construction depends on innovative strategies being developed by teachers and practitioners, made available to students and then professionally adopted. Successful transfer of this knowledge relies on appropriate support for both students and academics to ensure the new knowledge is translated into a format appropriate to the learner's current state of understanding, often using a constructivist, student-centred learning approach. This special issue of the journal Architectural Engineering and Design Management examines new strategies to manage effectively a growing number of students and a changing student profile in the built environment sector. Written by...
All the contributions to this volume are condensed versions of research projects undertaken by students in the final year of the online Master of Project Management degree delivered by the University of South Australia in conjunction with Open Universities Australia. Contributors to this book consist primarily of graduated Masters’ students, supported by supervising academics and relevant industry specialists and practitioners. As a result, the authors present current research interests across the breadth of Australia – with many of the perspectives demonstrating relevance to practice globally. The research perspectives presented here focus on four key themes of project management theory and practice: people and organisations; methodologies and practice domains; issues in application; and continuous improvement and benchmarking. Collectively, this work will be of particular interest to project management academics and researchers, post-graduate students, and the broader project management community.
Providing Peacekeepers analyzes the factors which encourage (or discourage) states from contributing their soldiers to serve in United Nations peacekeeping operations. It focuses on the UN's experiences during the twenty-first century and does so through four thematic and sixteen case study chapters.
This book constitutes the Proceeding of the Computational Intelligence in Information Systems conference (CIIS 2018), held in Brunei, November 16 - 18, 2018. The CIIS conference provides a platform for researchers to exchange the latest ideas and to present new research advances in general areas related to computational intelligence and its application. The 19 revised papers presented in this book have been carefully selected from 41 submissions. The Conference contributes to major fields of the Computing and Information Systems in theoretical and practical aspects. This include Computational Intelligence Techniques, Data Mining, Big Data, the Internet of Things (IoTs), Machine Learning, Predictive Analytics, Product and Design technology, Smart Products, Human Centered Design (HCD), Additive Manufacturing, Information Security, Computer Networks and Cyber Technologies.
1.1 OBJECTIVES • To determine the cost differences in materials utilized for conventional & precast buildings, as well as the proportion of materials wasted in the construction of commercial structure using precast & conventional technologies. • To determine the time and cost differences in commercial building construction using conventional versus precast techniques.
As businesses seek to compete on a global stage, they must be constantly aware of pressures from all levels: regional, local, and worldwide. The organizations that can best build advantages in diverse environments achieve the greatest success. Global Business Expansion: Concepts, Methodologies, Tools, and Applications is a comprehensive reference source for the latest scholarly material on the emergence of new ideas and opportunities in various markets and provides organizational leaders with the tools they need to be successful. Highlighting a range of pertinent topics such as market entry strategies, transnational organizations, and competitive advantage, this multi-volume book is ideally designed for researchers, scholars, business executives and professionals, and graduate-level business students.