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The inflammasome is a protein complex composed of an intracellular sensor—typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1β and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1β has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic optio...
A few clear factors are associated with living longer and healthier — such as higher levels of physical activity, good sleep patterns and proper nutrition. However, despite all the advances that have been made to increase the general population's physical activity, improve their sleep patterns, and boost their nutritional habits, there is still a lot to be done. This Research Topic aims to address the topic of healthy ageing and will consider manuscripts focused on the effects of improving these factors in all ages, from childhood to old age. We are mainly interested in questions of broader interventions at the individual (home settings), group (school, work, and gerontology settings), and societal level (community/based settings). We also welcome papers investigating the short- and long-term effects of environmental factors on physical changes in children, working and old age populations and their development. Correlational and survey studies examining the issues mentioned above are welcome.
Focusing on stunning paintings and engravings from around the world, 16 papers interrogate the driving forces behind global rock art research. Many of the motifs featured were created by indigenous hunter-gatherer groups; this book sheds new light on non-Western rituals and worldviews, many of which are threatened or on the point of extinction.
This reference book discusses the applications of microorganisms as a crucial solution for the sustainable management of toxic pollutants. It describes the microbial remediation of different kinds of pollutants like wastewater, antibiotics, and toxic chemicals. It highlights the technical, scientific, regulatory, safety, and societal impacts of various sustainable biodegradation approaches. The book describes various sensors in environmental pollution monitoring and pollutant detection. KEY FEATURES Provides a deep understanding of the use of sensors in environmental water monitoring and pollutant detection Covers exciting topics like biological upcycling of plastic wastes into value-added c...
Plasma Engineering is the first textbook that addresses plasma engineering in the aerospace, nanotechnology, and bioengineering fields from a unified standpoint. It covers the fundamentals of plasma physics at a level suitable for an upper level undergraduate or graduate student, and applies the unique properties of plasmas (ionized gases) to improve processes and performance over a wide variety of areas such as materials processing, spacecraft propulsion, and nanofabrication. The book starts by reviewing plasma particle collisions, waves, and instabilities, and proceeds to diagnostic tools, such as planar, spherical, and emissive probes, and the electrostatic analyzer, interferometric techn...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
The book is a multidisciplinary space and serves as a platform to share and learn about the frontier knowledge between different areas related to “Recent trends in sustainable engineering.” Sustainable engineering promotes the responsible use of resources and materials involved in the different manufacturing processes or the execution stages of a service. An interdisciplinary approach is required in all aspects of engineering. In this sense, engineers, researchers, and the academic community will play a fundamental role in developing new technologies that respect the environment, still, at the same time, that considers social and economic factors.