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Neurochemistry in Clinical Practice
This book offers a comprehensive overview of the most important neurochemicals and approaches everything from the neurochemical’s perspective. It attempts to integrate the biochemical pathways of synthesis and metabolism of these neurochemicals with the disease states and point out the avenues of diagnostic testing and therapeutic intervention. Each chapter focuses on a specific neurochemical and provides a brief history, the biochemical profile, metabolism, physiological functions, and the clinical aspects. The clinical part of each chapter includes a discussion on disease states with either increased or reduced activity of the neurochemical and either activation or inhibition of the relevant receptors. This book is targeted toward practitioners and students of neuroscience and is written to emphasize the importance of these neurochemicals in the brain. With this emphasis on background neurochemical processes, the readers will be pointed towards logical diagnostic studies, laboratory investigations, and therapies based on the neurochemical dysfunction that underlies various disease states.
Circulating Tumor Cells
It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis, establishing molecular targets, evaluating the efficacy of therapy, detecting the earliest signs of recurrence, and even detecting cancer at its earliest and most curable stages. The analysis of cancer through blood samples is now known as the liquid biopsy and has been a rich source of research and clinical application. There has been an explosion of interest and progress in liquid biopsy technologies since the first edition of this book. The second edition will expand its focus to now include not only circulating tumor cells (CTC), but also other em...
A New Era in Alzheimer's Research
A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals. - Contains basic knowledge about Alzheimer's disease and its causes and related pathology for a better understating of AD - Provides the multidisciplinary research on Alzheimer's disease in one source - Uniquely describes the details of the pathological, diagnostic, and preventive information for the potential development of novel anti-AD drugs - Includes hot topics, such as cerebrovascular pathology and lifestyle medicine, for the prevention of AD
Metacognition and Severe Adult Mental Disorders
Many adults who experience severe mental illness also suffer from deficits in metacognition - put simply, thinking about one’s own thought processes - limiting their abilities to recognize, express and manage naturally occurring painful emotions and routine social problems as well as to fathom the intentions of others. This book presents an overview of the field, showing how current research can inform clinical practice. An international range of expert contributors provide chapters which look at the role of metacognitive deficit in personality disorders, schizophrenia, and mood disorders, and the implications for future psychotherapeutic treatment. Divided into three parts, areas covered include: how metacognitive deficits may arise and the different forms they might take the psychopathology of metacognition in different forms of mental illness whether specific deficits in metacognition might help us understand the difficulties seen in differing forms of severe mental illness. Offering varying perspectives and including a wealth of clinical material, this book will be of great interest to all mental health professionals, researchers and practitioners.
