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Genetic Hearing Loss
Heredity, either alone or in combination with environmental factors, is the most prominent underlying cause of hearing impairment. Thanks in large part to positional cloning techniques, scientists have identified nearly 100 gene loci implicated in hearing loss since 1995-an extraordinarily rapid rate of gene identification. Genetic Hearing Loss branches into syndromic and nonsyndromic categorical directions in its coverage of the genetics behind hearing loss. Authored by 60 internationally recognized researchers, the book describes the normal development of the ear, updates the classification and epidemiology of hearing loss, and surveys the usage of audiometric tests and diagnostic medical examinations.
The Roots of Equality
This book investigates how Homo sapiens thrived in and nurtured a certain social condition that happened to abet our continual survival. This condition of individual autonomy shaped our species and led humans to demand social equality to this day.
Reflections on language evolution
This essay reflects on the fact that as we learn more about the biological underpinnings of our language faculty, the dominant evolutionary narrative coming out of the linguistic tradition most explicitly oriented towards biology ("biolinguistics") appears increasingly implausible. This text offers ways of opening up linguistic inquiry and fostering interdisciplinarity, taking advantage of new opportunities to provide quantitative, testable hypotheses concerning the complex evolutionary path that led to the modern human language faculty. The essay is structured around three main themes: (i) renewed appreciation for the comparative method applied to cognitive questions, leading to the identification of elementary but fundamental abstractions in non-linguistic species relevant to language; (ii) awareness of the conceptual gaps between disciplines, and the need to carefully link genotype and phenotype without bypassing any "intermediate" levels of description (certainly not the brain); and (iii) adoption of a "philosophical" outlook that puts the complexity of biological entities front and center.
The Routledge Handbook of the Ethics of Human Enhancement
The Routledge Handbook of the Ethics of Human Enhancement provides readers with a philosophically rich and scientifically grounded analysis of human enhancement and its ethical implications. A landmark in the academic literature, the volume covers human enhancement in genetic engineering, neuroscience, synthetic biology, regenerative medicine, bioengineering, and many other fields. The Handbook includes a diverse and multifaceted collection of 30 chapters—all appearing here in print for the first time— that reveal the fundamental ethical challenges related to human enhancement. The chapters have been written by internationally recognized leaders in the field and are organized into seven ...
Science, Politics, Stem Cells And Genes: California's War On Chronic Disease
Is there a way to fight back against 'incurable' disease? California thought so — and put its money where its mind was — three billion dollars' worth! And when that was gone, how about five and a half billion dollars more — to build and expand the California Institute for Regenerative Medicine?For some, science excites; it is the great adventure, to challenge the impossible: like a real-life battle with a giant squid, or the proposed disassembly of the Eiffel Tower, or ejecting from a jet in the sky, from a height greater than Mount Everest.For others, regenerative medicine is a mystery — could the urge to do murder have a genetic cause — which might be reduced?And for everyone, th...
Genome Research
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Biology in the Grid
How grids paved the way for our biological understanding of organisms As one of the most visual sciences, biology has an aesthetic dimension that lends force and persuasion to scientific arguments: how things are arranged on a page, how texts are interspersed with images, and how images are composed reflect deep-seated beliefs about how life exists on Earth. Biology in the Grid traces how our current understanding of life and genetics emerged from the pervasive nineteenth- and twentieth-century graphic form of the grid, which allowed disparate pieces of information to form what media theorist Vilém Flusser called “technical images.” Phillip Thurtle explains how the grid came to dominate...
Gene Regulatory Sequences and Human Disease
In Gene Regulatory Sequences and Human Disease, the Editor will introduce the different technological advances that led to this breakthrough. In addition, several examples will be provided of nucleotide variants in noncoding sequences that have been shown to be associated with various human diseases.
