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BioBuilder
"[P]rovides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories"--Page [4] of book cover
BioBuilder
Today’s synthetic biologists are in the early stages of engineering living cells to help treat diseases, sense toxic compounds in the environment, and produce valuable drugs. With this manual, you can be part of it. Based on the BioBuilder curriculum, this valuable book provides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories. It also serves as an introduction to the field for science and engineering enthusiasts. Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering t...
Zinc Finger Proteins
In the early 1980s, a few scientists started working on a Xenopus transcription factor, TFIIIA. They soon discovered a novel domain associated with zinc, and named this domain "zinc finger. " Th e number of proteins with similar zinc fingers grew quickly and these proteins are now called C2H2, Cys2His2 or classical zinc finger proteins. To date, about 24,000 C2H2 zinc finger proteins have been recognized. Approximately 700 human genes, or more than 2% of the genome, have been estimated to encode C2H2 finger proteins. From the beginning these proteins were thought to be numerous, but no one could have predicted such a huge number. Perhaps thousands of scientists are now working on C2H2 zinc f...
Inquiry-Based Learning for Science, Technology, Engineering, and Math (STEM) Programs
This volume covers the many issues and concepts of how IBL can be applied to STEM programs and serves as a conceptual and practical resource and guide for educators and offers practical examples of IBL in action and diverse strategies on how to implement IBL in different contexts.
Genome Refactoring
The science of biology celebrates the discovery and understanding of biological systems that already exist in nature. In parallel, the engineering of biology must learn how to make use of our understanding of the natural world to design and build new useful biological systems. ""Synthetic biology"" represents one example of recent work to engineer biological systems. This emerging field aims to replace the ad hoc process of assembling biological systems by primarily developing tools to assemble reliable-but-complex living organisms from standard components that can later be reused in new combination. The focus of this book is ""genome refactoring,"" one of several approaches to manage the co...
How to Build a Digital Library
How to Build a Digital Library reviews knowledge and tools to construct and maintain a digital library, regardless of the size or purpose. A resource for individuals, agencies, and institutions wishing to put this powerful tool to work in their burgeoning information treasuries. The Second Edition reflects developments in the field as well as in the Greenstone Digital Library open source software. In Part I, the authors have added an entire new chapter on user groups, user support, collaborative browsing, user contributions, and so on. There is also new material on content-based queries, map-based queries, cross-media queries. There is an increased emphasis placed on multimedia by adding a "...
Learning to Communicate in Science and Engineering
Case studies and pedagogical strategies to help science and engineering students improve their writing and speaking skills while developing professional identities. To many science and engineering students, the task of writing may seem irrelevant to their future professional careers. At MIT, however, students discover that writing about their technical work is important not only in solving real-world problems but also in developing their professional identities. MIT puts into practice the belief that “engineers who don’t write well end up working for engineers who do write well,” requiring all students to take “communications-intensive” classes in which they learn from MIT faculty ...
Financing the Entrepreneurial Venture
Financing the Entrepreneurial Venture focuses on financial management within entrepreneurial firms. Most of these are young firms, although some are more established. The book examines these firms at all phases of their life cycle, from the initial idea generation to the ultimate harvesting of the venture. The book covers firms in a diverse set of industries including high technology, low technology and services. A significant fraction of the cases focus on non-U.S. ventures. Additionally, the issues of gender and diversity are addressed in a number of settings.
