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Ion Channel Pharmacology
The improved understanding of ion channel structure, achieved through the use of molecular biology techniques, has opened the way for the development of new drugs targeted at specific types of ion channels. This book provides a comprehensive, single-volume overview of the effects of different drugs and toxins on ionic channels. The first part of the book deals with the development of ion channels, while subsequent chapters detail the electrophysiological properties and pharmacology of eight different types of ion channels, including intracellular, cyclic nucleotide-gated, and receptor operated channels. Drug effects in various cell types, along with the potential use of channels in therapeutics, are discussed for each channel type. Comprehensive and up-to-date, Ion Channel Pharmacology is an essential reference for every investigator in this fast-growing area of research.
Handbook of Ion Channels
The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce
Restrições à Antecipação de Tutela
O tema proposto refere-se à análise, dentro do contexto das tutelas antecipadas, dos seus pressupostos positivos e negativos, de algumas das restrições impostas pela legislação vigente a hipóteses de concessão, bem como à viabilidade da sua aplicação na situação atual da sua interpretação pela doutrina e pela jurisprudência. Procurou-se demonstrar a aplicação dessas normas restritivas, bem como a justificativa para a sua aceitação dentro do conceito da segurança jurídica e do contexto fático em que cada um dos casos analisados está inserido. Ademais, foi desenvolvido estudo crítico sobre as hipóteses em que se admite a relativização dessas restrições, as razões que levam a tal resultado e as consequências daí advindas para o cenário jurídico brasileiro. Todos os pontos mencionados foram baseados principalmente na análise do direito das partes a uma tutela jurisdicional efetiva e tempestiva, sempre com enfoque no direito processual constitucional, destacando-se a importância do respeito ao devido processo legal nesses casos e a importância de se garantir à parte um processo célere e de duração razoável.
Direito em Debate – Vol. II
A série Direito em Debate convida o leitor a refletir sobre temas atuais por meio de estudos consistentes, plurais e dinâmicos, que percorrem temas relevantes e interdisciplinares, lançando mão de explanações lúcidas e consistentes. Como resultado, os artigos aqui apresentados conduzem o estudioso à construção do arcabouço da doutrina exposta, bem como o incentiva a navegar pela estrada, por vezes tortuosa, de alternativas práticas.
Dermatophytes and Dermatophytoses
This book provides a comprehensive overview on the most recent knowledge in dermatophytic infection biology. Topics covered range from taxonomy, biology and genetics of most common skin disease causing fungi over immunology of dermatophytosis to diagnosis and treatment approaches. Furthermore epidemiology of skin diseases caused by pathogenic fungi is discussed. The book is aimed at researchers and advanced students in infection biology, microbiology and dermatology.
Manual of Small Animal Anesthesia
Here's the updated practical guide to small animal anesthetic principles and techniques. A concise outline format makes it easy for readers to find information. The 2nd Edition synthesizes current literature and clinical research*as well as new developments in drugs, equipment, and techniques*to offer a wide spectrum of up-to-date management choices.
Animal V: Executioner's Song
When the Grand Design is finally revealed it will spell the last ride for Mr. Armed and Brokenhearted. In this final installment of the widely popular “Animal” series, we find our anti-hero on a hunt for the woman who forced him to pick his guns back up when she burned his entire world down. The traitorous, Red Sonja. She alone holds the key to saving his children and avenging his murdered wife, Gucci, but first he has to find her. To do this, Animal reassembles his old gang: The Dog Pound for what will prove to be their most dangerous mission yet. The stakes are higher than ever and not everyone is expected to make it, but the members of the Pound readily accept the task and the risks t...
