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The past decades have seen major developments in the understanding of the cellular and molecular biology of cancer. Significant progress has been achieved regarding long-term survival for the patients of many cancers with the use of tamoxifen for treatment of breast cancer, treatment of chronic myeloid leukaemia with imatinib, and the success of biological drugs. The transition from cytotoxic chemotherapy to targeted cancer drug discovery and development has resulted in an increasing selection of tools available to oncologists. In this Special Issue of Pharmaceuticals, we highlight the opportunities and challenges in the discovery and design of innovative cancer therapies, novel small-molecu...
The most comprehensive resource for students on EU competition law; extracts from key cases, academic works, and legislation are paired with incisive critique and commentary from an expert author team.
The European Community has pledged respect for the cultural and linguistic diversity of its Member States and has recognized minority languages as an inherent constituent in this regard. This development reflects a broader trend within the Community towards grappling with less obvious aspects of supranational governance. Minority language groups turn optimistically to `Europe' in response. But, despite rhetorical promises, just what can the EC actually be expected to do in the realm of minority language protection, a politically sensitive and traditionally domestic concern? Arguments put forward to date focus primarily on philosophical, moral, economic, and political discourse. While these considerations are a vital aspect of the debate on minority languages and on linguistic diversity more generally, the question of legal basis remains largely unanswered. For the first time, this book traces comprehensively the existence of an appropriate legal basis for action undertaken by the EC in this domain, striving in particular to locate a pragmatic yet effective balance between legitimate possibility and acceptable limitations.
This book is the product of a research program that provided the opportunity for natural scientists, socio-economic scientists and lawyers to gather and discuss the North Sea ecosystem.
An accessible and innovative look at Irish history by some of today's most exciting historians of Ireland This book brings together some of today's most exciting scholars of Irish history to chart the pivotal events in the history of modern Ireland while providing fresh perspectives on topics ranging from colonialism and nationalism to political violence, famine, emigration, and feminism. The Princeton History of Modern Ireland takes readers from the Tudor conquest in the sixteenth century to the contemporary boom and bust of the Celtic Tiger, exploring key political developments as well as major social and cultural movements. Contributors describe how the experiences of empire and diaspora ...
This history of the structure and organization of the solicitors' profession on Ireland focuses on the growth and trajectory of the Law Society of Ireland from its 1852 founding of its predecessor the Society of Attorneys and Solicitors in Ireland to the present. Hall (chief legal officer for Eircom
Essays in Irish Labour History is a tribute to the late Professor John W Boyle, University of Guelph, Canada and a leading practitioner of Irish labour history, and his late wife Elizabeth. Boyle's specialism was in nineteenth century labour history, with a particular emphasis on Dublin and Belfast, cities to which he had academic and personal attachments, and these interests are well reflected in this book. The history of labour in Ulster is especially well covered, as is that of Protestant workers throughout the island. The collection also includes substantial scholarly articles that reflect ongoing research and areas that have thus far been neglected, such as the place for casual labour in nineteenth century Ireland and the impact of religion on the Irish Labour Party, 1922-73. The range of topics is broad and includes an obituary essay on the Boyles and an interrogation of Irish historiography and the working class.
Ireland has been shaped by centuries of emigration as millions escaped poverty, famine, religious persecution, and war. But what happens when we reconsider this well-worn history by exploring the ways Ireland has also been shaped by immigration? From slave markets in Viking Dublin to social media use by modern asylum seekers, Migration and the Making of Ireland identifies the political, religious, and cultural factors that have influenced immigration to Ireland over the span of four centuries. A senior scholar of migration and social policy, Bryan Fanning offers a rich understanding of the lived experiences of immigrants. Using firsthand accounts of those who navigate citizenship entitlements, gender rights, and religious and cultural differences in Ireland, Fanning reveals a key yet understudied aspect of Irish history. Engaging and eloquent, Migration and the Making of Ireland provides long overdue consideration to those who made new lives in Ireland even as they made Ireland new.