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Current Topics in Developmental Biology
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Cell Hybrids summarizes the methodology of cell fusion-the fusion of human, animal, and plant cells of different origins to produce cell hybrids-and surveys the main applications and current findings of the hybridization technique. The book opens with a chapter on the history cell hybridization. This is followed by separate chapters on spontaneous cell fusion, virus-induced cell fusion, the cell fusion mechanism, regulation of DNA synthesis and mitosis in heterokaryons and homokaryons, and regulatory events which occur when two cells with different nuclear activity and/or phenotype are fused with each other. Subsequent chapters deal with methods used in preparing various cell fragments and some of their properties and uses in fusion experiments; isolation of growing hybrid cells; chromosome patterns and phenotypic expression in hybrid cells; cell organelles in hybrid cells; analysis of malignancy by cell hybridization. The final chapters discuss the use of somatic cell hybridization to analyze the interaction between a number of viruses and their host cells; and the use of plant cell hybrids.
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The Amino Sugars: The Chemistry and Biology of Compounds Containing Amino Sugars, Volume IIA: Distribution and Biological Role focuses on the chemistry, physical chemistry, and biochemistry of naturally occurring and synthetically prepared amino sugars and amino sugar-containing molecules, as well as the biological and medical importance of these molecules. The selection first offers information on the distribution of amino sugars in microorganisms, plants, and invertebrates and amino sugars and macromolecules containing amino sugars in liver. Discussions focus on microorganisms, invertebrates, amino sugar composition, catabolism of amino sugars, and metabolic interrelationships between amin...
Cell Biology, A Comprehensive Treatise, Volume 3: Gene Expression: The Production of RNA's mainly discusses the molecular and cytological bases of gene expression. The coverage begins with the concepts of organization of DNA and gene sequences in chromosomes, as an introduction to a more detailed coverage of gene expression. The book opens with a general discussion on the organization of DNA sequences in chromosomes. This chapter includes different methods of analyzing DNA sequences. As the book progresses, it looks upon the details on gene reiteration and amplification up to the transcription of prokaryotes and eukaryotes. It includes the ways of regulating transcription. The following chap...