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HIV-1 Integrase
  • Language: en
  • Pages: 710

HIV-1 Integrase

This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.

HIV I: Molecular Biology and Pathogenesis: Clinical Applications
  • Language: en
  • Pages: 561

HIV I: Molecular Biology and Pathogenesis: Clinical Applications

The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, ...

Federal Register
  • Language: en
  • Pages: 852

Federal Register

  • Type: Book
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  • Published: 1999
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  • Publisher: Unknown

None

Drug-Nucleic Acid Interactions
  • Language: en
  • Pages: 740

Drug-Nucleic Acid Interactions

  • Type: Book
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  • Published: 2001-07-31
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  • Publisher: Elsevier

This volume consolidates the key methods for studying ligand-nucleic acid interactions into a convenient source. Techniques that are examined range from biophysical and chemical approaches to methods rooted in molecular and cell biology.

Frontiers in Medicinal Chemistry , Volume (1)
  • Language: en
  • Pages: 680

Frontiers in Medicinal Chemistry , Volume (1)

""Frontiers in Medicinal Chemistry" is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. "Frontiers in Medicinal Chemistry" covers all the areas of medicinal chemistry, incl"

Advances in Virus Research
  • Language: en
  • Pages: 502

Advances in Virus Research

Advances in Virus Research

Cardiovascular Pharmacology: Heart and circulation
  • Language: en
  • Pages: 344

Cardiovascular Pharmacology: Heart and circulation

Cardiovascular disease remains a major cause of death and disability in developed countries and, increasingly so, in the developing world. Presented in this volume of Advances in Pharmacology are some of the most promising possibilities for treating large numbers of individuals afflicted with these conditions. Contains up-to-date reviews of the most important emerging cardiovascular therapies written by world leaders in the field

Plant Bioactives and Drug Discovery
  • Language: en
  • Pages: 600

Plant Bioactives and Drug Discovery

An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound is...

Molecular Carcinogenesis and the Molecular Biology of Human Cancer
  • Language: en
  • Pages: 592

Molecular Carcinogenesis and the Molecular Biology of Human Cancer

  • Type: Book
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  • Published: 2005-10-31
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  • Publisher: CRC Press

To gain a complete overview of what is presently known about molecular carcinogenesis would prove to be a very daunting task for those not already steeped in this complex subject. Fortunately, David Warshawsky and Joseph Landolph Jr., both highly respected for their own contributions to the field, know exactly whom to call upon to fulfill the need

Dendrimer-Based Drug Delivery Systems
  • Language: en
  • Pages: 542

Dendrimer-Based Drug Delivery Systems

The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug de...