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Mediterranean Israeli Music and the Politics of the Aesthetic
"An ethnographic study of the emergence of a pan-ethnic style of music in Israel between the mid-1970s and mid-1990s. This two-decade period encompasses the coming of age of the Middle Eastern and North African creators of the grassroots music network in the 1970s and the sea change in the music's reception by mainstream Israeli society in the 1990s.
Precision Vaccinology for Infectious Diseases
The Human body is a vast network of interacting genes, proteins, and metabolites. These components, which may be considered host factors, change under disease, treatment or healthy condition. While treatment of many diseases depends on therapeutic drugs, vaccines remain the most effective long-term public health intervention to prevent infectious diseases. To date, vaccines have been developed to treat entire populations with little provision for predisposing individual host factor differences. However, the use and application of vaccines is facing multiple challenges with increasing numbers of vaccine non-responders and vaccine-relapsed individuals. The cause of this complication is partially due to host-factors. Another challenge is the adverse effects of vaccines in patients with primary immunodeficiency or autoimmune diseases, as well as vaccine-waning immunity in ageing populations, obese populations, or those with co-infection. To overcome these challenges, the solution may be the design, and formulation of precision vaccines, which are patient-specific.
The Neonatal Immune System: A Unique Host-Microbial Interface
Emerging from the protective environment of the uterus, the newborn is exposed to a myriad of microbes, and quickly establishes a complex microbiome that shapes the infant’s biology in ways that are only now beginning to come to light. Among these exposures are a number of potential pathogens. The host responses to these pathogens in the neonatal period are unique, reflecting a developing immune system even with delivery at term. Preterm infants are delivered at a time when host defense mechanisms are even less developed and therefore face additional risk. As such, the organisms that cause disease in this period are different from the pathogens that are common in other age groups, or the d...
On God, Space, and Time
For Akiva Jaap Vroman "a day in the infinite past" is nonsense. All the days that have elapsed belong to a past of countable days; they started on a first day a finite number of days ago. Time began this first day. It follows that an eternal past does not exist. Vroman bases his reasoning on a simple mathematical law: an infinite quantity remains the same infinite quantity if a finite quantity, however large, is subtracted from it. On God, Space, and Time devotes itself to this proof.On God, Space, and Time is rooted in the epistemological thinking of Immanuel Kant and Jean Piaget and the law of Leucippus, and draws from the somewhat disparate fields of psychology, physiology, mathematics, and physics.
Recent Advances in Precision Vaccine Discovery & Development
Topic Editor Jay Evans is the co-founder, President and CEO of Inimmune Corporation. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Reinventing Project Management
Projects are the engines that drive innovation from idea to commercialization. In fact, the number of projects in most organizations today is expanding while operations is shrinking. Yet, since many companies still focus on operational excellence and efficiency, most projects fail—largely because conventional project management concepts cannot adapt to a dynamic business environment. Moreover, top managers neglect their company's project activity, and line managers treat all their projects alike—as part of operations. Based on an unprecedented study of more than 600 projects in a variety of businesses and organizations around the globe, Reinventing Project Management provides a new and highly adaptive model for planning and managing projects to achieve superior business results.
