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Genetics and Auditory Disorders
Genetics is fundamental to hearing function, and an understanding of genetics enhances both auditory research and the clinical treatment of the hearing impaired. Approaches to the diagnosis and treatment of hearing impairment have developed from technological advances in genetic research. This volume covers gene expression, mutations, mapping and cloning, as well as mitochondrial and cellular genetics. Chapters are also included on the uses of mouse models, genetic epidemiology and genetic counseling specifically for hearing impairment. As a comprehensive review of the genetics of hearing, this book will interest hearing researchers, clinicians and genetic counselors.
Solution Art
Counselling, therapy, and coaching always work with the use of language. With art-oriented approaches, the limitations of language can be overcome. One of the most important works of expressive arts therapy, Lösungskunst is now available in English translation. The key concept of intermodality- the authors' term for oscillation between art-analog methods- combines with the primary focus on resources and strong emphasis on solutions to lay the groundwork for the method that is as vital now as it was originally. The importance of imagination, artistic and aesthetic experience to mental wellbeing is showcased, challenging the common focus on the cognitive and emotional facets of mental health. In-depth case studies and explanations illuminate the origins and use of the theoretical frameworks, helping experienced practitioners and trainees alike to engage with the fundamental methods and concepts of expressive arts therapy.
Genetic Hearing Impairment
A decade of innovative findings in the research of molecular biology of hearing and deafness is reflected in this volume. The genetic causes for many types of syndromic and non-syndromic deafness are identified and genotypic-phenotypic relationships are explored. Although the type and degree of deafness caused by mutations in different genes significantly overlap, relatively unique age-related audiometric profiles are also emerging. For example, the audioprofile of DFNA1 and DFNA6-14 is a low-frequency sensorineural hearing loss; with DFNA8-14 it is a mid-frequency sensorineural hearing loss, and with DFNA2, DFNA5 and DFNA20-26 it is a high-frequency progressive hearing loss. Recognizing such audioprofiles can facilitate well-guided decision-making in clinical practice and can direct genetic testing for deafness. With an accurate genetic diagnosis, prognostic information can be provided to patients and their families. In the future, gene-specific habilitation options may also become available. To keep up to date with new clinical standards of diagnosing genetic hearing impairment, this book is indispensable reading to otorhinolaryngologists and audiologists.
Art in Reproduction
This illuminating study examines the cultural meaning of artistic reproduction in a refreshingly new context through its consideration of how three artists managed the reproduction of their work.
Genetics in Otorhinolaryngology
How can genetics be useful to general otorhinolaryngologists and their patients? This book summarizes the most recent information on genetic diseases, including deafness and head-and-neck cancer, that is relevant to clinical practice, particularly with reference to accurate genetic counseling. The first part of the volume presents a basic and general review of genetics. Up-to-date information on deafness genes is given and the mouse model for hearing impairment is thoroughly described. The application of molecular analysis of head-and-neck carcinoma has been one of the fundamental breakthroughs in understanding the cell biology of the carcinoma. Two chapters are devoted to the discussion of tumor suppressor genes and oncogenes. This book is highly recommended since genetics, particularly molecular genetics, is still an unfamiliar subject to otorhinolaryngologists.Yet there is a constant need to be alert to the possibility of diagnosing hereditary disorders and to obtain genetic consultation for a complete evaluation. A comprehensive list of references is given for those who wish to find more detailed information.
Genetic Hearing Loss
Heredity, either alone or in combination with environmental factors, is the most prominent underlying cause of hearing impairment. Thanks in large part to positional cloning techniques, scientists have identified nearly 100 gene loci implicated in hearing loss since 1995-an extraordinarily rapid rate of gene identification. Genetic Hearing Loss
Copper-Containing Molecules
A wide range of researchers are currently investigating different properties and applications for copper-containing proteins. Biochemists researching metal metabolism in organisms ranging from bacteria to plants to animals are working in a completely different area of discovery than scientists studying the transportation and regulation of minerals and small molecule nutrients. They are both working with copper-containing proteins, but in very different ways and with differing anticipated outcomes.
Plant Cold Hardiness
This volume is compiled based on the proceedings of the 5th International Plant Cold Hardiness Seminar, which was held at Oregon State University, Corvallis, Oregon, USA, August 5 to 8, 1996. Participants representing 16 nations and 22 U. S. states attended the seminar. Researchers came from major laboratories around the world involving plant cold hardiness research. The information compiled in this volume represents the state-of the-art research and our understanding of plant cold hardiness in terms of molecular biol ogy, biochemistry, and physiology. The 1996 International Plant Cold Hardiness Seminar was the fifth of the series; it was first held in 1977 at the University of Minnesota, St...
