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Proceedings of the 11th European Society for Neurochemistry Meeting held in Groningen, The Netherlandes, June 15-20, 1996
Animal models of neuro- and psychopathological states in humans are an indispensable part of both experimental neurology and biological psychiatry. Written by a team of experts, this book provides an up-to-date detailed overview of the current approaches to the design of viable animal models for eight prominent neuropsychiatric diseases. The book is specifically written with the research-oriented reader in mind — both in academia and the pharmaceutical industry. It contains first-hand information on how to design viable animal models for Alzheimer's disease, epilepsy, Huntington's disease, Parkinson's disease, addiction, depression, fear and anxiety, and schizophrenia. Each chapter also critically discusses the limitations of the animal experimental approach towards an understanding of human neuropsychiatric disorders.The book is an essential source of reference for researchers who seek to successfully continue and elaborate the experimental work that will finally lead to a better understanding of the neurobiological basis of the diseases, as well as to an improvement of both diagnosis and therapy.
The two Animal Models in Psychiatry volumes are loosely organized by subject. The first volume contains a number of chapters concerned with schizophrenia, psyc- ses, neuroleptic-induced tardive dyskinesias, and other d- orders that may involve dopamine, such as attention deficit disorder and mania. The second volume deals with affective and anxiety disorders, but also includes chapters on subjects not easily classified as either psychotic, or affective, or an- ety-related, such as aggression, mental retardation, and memory disorders. Four chapters on animal models of schizophrenia or psychoses are included in the present v- ume because of the importance of these disorders in p- chiatry. Like...
A detailed account of the neurobiological mechanisms of satiety, this book covers the neural, endocrine, and cellular underpinnings of the process through which we stop eating. Authors expert in different aspects of the process have provided succinct, critical reviews of recent progress and current problems in the field.
This handbook presents a diverse range of effective treatment approaches for individuals with intellectual and developmental disabilities (IDD). Its triple focus on key concepts, treatment and training modalities, and evidence-based interventions for challenging behaviors of individuals with IDD provides a solid foundation for effective treatment strategies, theory-to-implementation issues, and the philosophical and moral aspects of care. Expert contributions advocate for changes in treating individuals with intellectual and developmental disabilities by emphasizing caregiver support as well as respecting and encouraging client autonomy, self-determination, and choice. With its quality-of-li...
Modern Synthesis Processes and Reactivity of Fluorinated Compounds focuses on the exceptional character of fluorine and fluorinated compounds. This comprehensive work explores examples taken from all classes of fluorine chemistry and illustrates the extreme reactivity of fluorinating media and the peculiar synthesis routes to fluorinated materials. The book provides advanced and updated information on the latest synthesis routes to fluorocompounds and the involved reaction mechanisms. Special attention is given to the unique reactivity of fluorine and fluorinated media, along with the correlation of those properties to valuable applications of fluorinated compounds. - Contains quality content edited, and contributed, by leading scholars in the field - Presents applied guidance on the preparation of original fluorinated compounds, potentially transferable from the lab scale to industrial applications - Provides practical synthesis information for a wide audience interested in fluorine compounds in many branches of chemistry, materials science, and physics
This book presents the Proceedings from the First International Conference on Ibogaines, held in November of 1999 at New York University's School of Medicine. In essence, it presents significant new data on neurobiological, clinical, sociocultural, and policy aspects of ibogaine. Ibogaine is a natural product derived from the bark of the root of the African shrub Tabernathe iboga. It has a history of use as a medicinal and ceremonial agent in West Central Africa, and has been alleged to be effective as a treatment for substance dependence. The study of Ibogaine may shed light on the neurobiology of addiction and lead to the development of new medication for the treatment of addiction. Curren...
The new edition of Complete Psychology is the definitive undergraduate textbook. It not only fits exactly with the very latest BPS curriculum and offers integrated web support for students and lecturers, but it also includes guidance on study skills, research methods, statistics and careers. Complete Psychology provides excellent coverage of the major areas of study . Each chapter has been fully updated to reflect changes in the field and to include examples of psychology in applied settings, and further reading sections have been expanded. The companion website, www.completepsychology.co.uk, has also been fully revised and now contains chapter summaries, author pages, downloadable presentations, useful web links, multiple choice questions, essay questions and an electronic glossary. Written by an experienced and respected team of authors, this highly accessible, comprehensive text is illustrated in full colour, and quite simply covers everything students need for their first-year studies as well as being an invaluable reference and revision tool for second and third years.
The introduction of chlorpromazine in 1953, and haloperidol in 1958, into clinical practice dramatically altered the therapy of schizophrenic patients. Although representing by no means a cure for this severe psychiatric ill ness, it allowed, for the first time, to adequately control the severe hallu cinations and delusional beliefs which prevent these patients from leading a more or less independent life. Indeed these antipsychotics (and the many congeners that were to follow) significantly reduced the number ofchronic schizophrenic inpatients in psychiatric clinics all over the world. However soon after their introduction it became clear that, like all other available drugs, antipsychotics...