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In 2017, a mysterious interstellar object transited the Solar System. Called 'Oumuamua, the Hawaiian word for "scout," it buzzed past the inner worlds, bound for deep space. By the time it was noticed, it had already passed Earth. It was soon forgotten, dismissed as a comet or planetary fragment. Earth's scientists turned to more pressing matters. But 'Oumuamua was no mere rock. An alien spaceship looking for habitable planets, it sent a machine probe to Earth, containing a quantum computer. After crash landing in South America, the probe was found by tech billionaire Christian Becker, who used its computational power to give himself groundbreaking technology and unlimited wealth. . . . Until something goes wrong. War veteran Will Logan is kidnapped and brought to Becker's highly secret research campus. Becker is certain that Will and his missing wife, Alex, are the saboteurs. But nothing is what it seems . . .
TRINITY'S LEGACY is the first in a trilogy which takes readers on a thrilling road trip full of high tech, drama and twists as humanity encounters an alien species for the first time. It is an official semi-finalist for the 2018 CYGNUS Book Awards for Science Fiction. The sequel, TRINITY'S FALL will be released later this year, with TRINITY: EXTINCTION planned for 2020.The Vu-Hak: An ancient and malevolent alien race, once organic, now entities of pure thought, drifting between the stars, limitless and immortal. An alpha species. A species that colonises on a galactic-scale.The portal: A rift in space connecting Earth to the Vu-Hak galaxy. A result of the Cold War's secret nuclear arms race....
The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover all major available information about these materials, both still on experimental levels and already applied in patients.
An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.
This text introduces the chemistry, characterization and application of polyphosphoesters including comprehensive coverage of poly(alkylene H-phosphonate)s, poly(alkylene phosphate)s, poly(alkyl or aryl phosphonate)s, and poly(alkyl phosphite)s and poly(alkyl phosphinite)s.
DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topics include carcinogenesis as a predictive and/or prognostic biomarker for cancer therapy, nucleotide excision repair, and tumor genetics and personalized medicine. The contributions provide essential information to scientists, pharmaceutical investigators, and clinicians interested in cancer therapy.
A handy reference guide to living with fatigue! Medical Etiology, Assessment, and Treatment of Chronic Fatigue and Malaise: Clinical Differentiation and Intervention is the single reference source you need for vital information on the fatiguing illnesses that affect more than 800,000 Americans. Written by one of the foremost experts in the field, the book is a comprehensive guide to the debilitating, and often misunderstood, phenomenon of fatigue, examining its multiple causes and treatments. Through a detailed history of chronic fatigue and a look at the factors that influence evaluation, diagnosis, and treatment, the book gives you immediate access to the answers you—and your patients—...
Ovarian cancer is not only the commonest but also the most lethal gynaecological malignancy, partly because the majority of patients present with advanced disease. Nevertheless, the management of patients with ovarian neoplasms has changed substantially recently, with improved survival due to better screening strategies, major advances in chemotherapy and the constantly evolving role of surgery. Optimal patient care is best achieved by a multidisciplinary team, with imaging playing a pivotal role. The explosion of technological developments in imaging in recent years has meant that all members of the team should understand the potential applications, limitations and advantages of evolving imaging techniques. Each volume in Contemporary Issues in Cancer Imaging - A Multidisciplinary Approach is edited by an expert guest editor with contributions from all members of the multidisciplinary team, thus bringing together expertise from many specialties to promote the understanding and application of modern imaging in overall patient management.
Smart Materials for Drug Delivery brings together the recent findings in the area and provides a critical analysis of the different materials available and how they can be applied to advanced drug delivery systems.
Cutting edge reviews by leading researchers illuminate key aspects of DNA repair in mammalian systems and its relationship to human genetic disease and cancer. Major topics include UV and X-Ray repair, repair of chemical damage, recombinational repair, mismatch repair, transcription-repair coupling, and the role of DNA repair in disease prevention. Extensive up-to-date references and rigorous peer-review of each chapter make this volume definitive and bring it to the active frontiers of research.