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This volume provides a variety of technical approaches to study dopamine system function and dysfunction. Chapters guide readers through dopamine release in ex vivo and freely moving animals, multi-recording devices for in vivo simultaneous single cell and population activity, in silico modeling of dopamine neurons activity, neuroanatomical approaches, unbiased stereology, ultrastructural analyses of dopaminergic neurons, and axonal innervation. Additionally, chapters also incorporate pharmacological tools to model neuropsychiatric diseases, novel behavioral paradigms to dissect dopamine's role in behavior, and functional imaging to follow human dopamine system development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, Dopamine Neurotransmission aims to be a valuable resource for researchers in various disciplines.
Sleep Disorders Part 1 offers a glimpse of developments that focus on diagnostic techniques in the field of neurobiology of sleep. This part discusses the models of the rapid eye movement (REM) sleep mechanism; issues regarding sleep states, stages, and memory consolidation; and advances in the understanding of the sleep-wake genes, gene products, the circadian clock, and the role of sleep duration. This book explains noninvasive neuroimaging studies, particularly positron emission tomographic and single photon emission computed tomographic scans. It further discusses advances in clinical science, including concepts about neurobiology of sleep, narcolepsy-cataplexy, therapy, and laboratory t...
Brain mechanisms for arousal, alertness, and attention underlie all cognitive functions and all emotional expression. This volume discusses the neuroanatomy, neurophysiology, and functional genomics of these states, and the medical consequences of their damage in human patients -- e.g. vegetative states, attention deficit hyperactivity disorder, autism, age-related dementias, mood disorders and sleep disorders. The volume also discusses problems related to vigilance, environmental toxins, fatigue states, circadian rhythms, and sleep/wake physiology, and presents and discusses relevant research techniques, with an emphasis on molecular genetics and on human and animal behavior. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.
El libro Prácticas docentes en Educación Continua Universitaria recopila el trabajo de 24 docentes, profesionales y personas dedicadas a la investigación, quienes han realizado un esfuerzo por reflexionar, sistematizar, documentar y compartir sus prácticas docentes. Desde diversas disciplinas, esta publicación incluye un conjunto de experiencias y prácticas, propuestas metodológicas, recursos de aprendizaje y bibliografía actualizada para que lectores y lectoras puedan avanzar en la reflexión acerca de sus propias prácticas docentes. Esperamos que sea el primer paso de un largo camino de aprendizaje generoso, creativo y colaborativo que permita contribuir desde la diversidad de exp...
The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with “wide awake” EEG patterns and EMG suppression. The first report linking REM sleep to a pathology occurred in 1961 and a clear association of sleep onset REM periods, cataplexy, hypnagogic hallucinations and sleep paralysis was fully established by 1966. When a naïve individual happens to ob...