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This tutorial will help technical professionals in optics determine whether their technologies have potential application in the life sciences. It also is useful as a 'prep class' for more detailed books on biology and biotechnology, filling the gap between fundamental and high-level approaches.
A shocking exposé of the reckless proliferation of bio-weapon research and the threat this poses to everyday Americans. Battling a new generation of corporate giants and uncovering threats right in our own backyard, Kenneth King’s Germs Gone Wild reveals the massive expansion of America's bio-defense research labs and the culture of deception surrounding hundreds of facilities that have opened since 9/11. King experienced the menace of bio-defense research firsthand when local government and business leaders tried to lure a new facility to his hometown in Kentucky. Researching the safety claims, he not only found many of them to be completely false, but was also horrified by the lack of o...
Biological warfare agent (BWA) detectors are designed to provide alerts to military personnel of the presence of dangerous biological agents. Detecting such agents promptly makes it possible to minimize contamination and personnel exposure and initiate early treatment. It is also important, though, that detectors not raise an alarm when the situation does not warrant it. The question considered in this book is whether Agent-Containing Particles per Liter of Air (ACPLA) is an appropriate unit of measure for use in the evaluation of aerosol detectors and whether a better, alternative measure can be developed. The book finds that ACPLA alone cannot determine whether a health threat exists. In order to be useful and comparable across all biological agents and detection systems, measurements must ultimately be related to health hazard. A Framework for Assessing the Health Hazard Posed by Bioaerosols outlines the possibility of a more complex, but more useful measurement framework that makes it possible to evaluate relative hazard by including agent identity and activity, particle size, and infectious dose.
The manipulation of pictures and video in digital form has been an established research activity for more than twenty years. It is only recently, however, that digital image and video processing equipment has been accessible to the gen eral public. This is due in part to the rapidly growing economy. of the home computer. A major contributing factor has been the marked rise in the pres ence of the non-academic user on the internet, particularly the World Wide Web (WWW). Manipulating digital imagery has become synonymous with the WWW. It is the drive to present audio and visual media to the home user in an interactive form and to increase the available range of choices, which has encouraged ag...
On March 10-11, 2016, the National Academies of Sciences, Engineering, and Medicine held a public symposium on potential U.S. government policies for the oversight of gain-of- function (GOF) research. This was the Academies' second meeting held at the request of the U.S. government to provide a mechanism to engage the life sciences community and the broader public and solicit feedback on optimal approaches to ensure effective federal oversight of GOF research as part of a broader U.S. government deliberative process. The first symposium, held in December 2014, examined the underlying scientific and technical questions surrounding the potential risks and benefits of GOF research involving pathogens with pandemic potential. The second symposium focused on discussion of the draft recommendations regarding GOF research of a Working Group of the National Science Advisory Board for Biosecurity. This report summarizes the key issues and ideas identified during the second symposium.
Ten years after the publication of Infrared Optics and Zoom Lenses, this text is still the only current publication devoted exclusively to infrared zoom lenses. This updated second edition includes 18 new refractive and reflective infrared zoom systems, bringing the total number of infrared zoom optical systems to 41 systems. Other additions include a section on focal plane arrays and a new closing chapter specifically devoted to applications of infrared zoom lenses. Coverage of wavelength region has been expanded to include the near infrared. Additional topics include an examination of the importance of principal planes, methods for athermalization by means of computer glass substitution, and global optimization techniques for zoom lens design.
Infectious diseases have existed longer than us, as long as us, or are relatively newer than us. It may be the case that a disease has existed for many, many years but has only recently begun affecting humans. At the turn of the century the number of deaths caused by infections in the United States had been falling steadily but since the '80s has seen an increase. In the past 30 years alone 37 new pathogens have been identified as human disease threats and 12% of known human pathogens have been classified as either emerging or remerging. Whatever the story, there is currently a "war" on infectious diseases. This war is simply the systematic search for the microbial "cause" of each disease, f...
This volume is the latest in a series of biennial assessments of the scientific and technical quality of the Army Research Laboratory (ARL). The current report summarizes findings for the 2007-2008 period, during which 95 volunteer experts in fields of science and engineering participated in the following activities: visiting ARL annually, receiving formal presentations of technical work, examining facilities, engaging in technical discussions with ARL staff, and reviewing ARL technical materials. The overall quality of ARL's technical staff and their work continues to be impressive, as well as the relevance of their work to Army needs. ARL continues to exhibit a clear, passionate concern fo...
Vector-borne infectious diseases, such as malaria, dengue fever, yellow fever, and plague, cause a significant fraction of the global infectious disease burden; indeed, nearly half of the world's population is infected with at least one type of vector-borne pathogen (CIESIN, 2007; WHO, 2004a). Vector-borne plant and animal diseases, including several newly recognized pathogens, reduce agricultural productivity and disrupt ecosystems throughout the world. These diseases profoundly restrict socioeconomic status and development in countries with the highest rates of infection, many of which are located in the tropics and subtropics. Although this workshop summary provides an account of the indi...