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This volume provides a comprehensive overview of hematologic issues that clinicians regularly encounter in the critical care environment. The text features hematologic scenarios that affect the adult ICU patient, outlines pathogenesis and challenges associated with the hematologic disorder, and offers treatment modalities. Hematologic issues covered include anemia, hemostatic abnormalities, and risks of transfusion. The book also details challenges in specific ICU populations, such as patients afflicted with liver disease, brain injury, sepsis, cardiovascular disease, malignancy, and trauma. Written by experts in the field, Hematologic Challenges in the Critically Ill is a valuable resource for clinicians in the critical care environment who treat critically ill patients afflicted with hematologic complications.
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Misinformation is one of the twenty-first century’s greatest challenges, a peril to democracy, peace, science, and public health. Yet we lack a clear understanding of what makes misinformation so potent and why it can spread so rapidly. In Falsehoods Fly, a leading cognitive scientist and philosopher offers a new framework for recognizing and countering misleading claims by exploring the ways that information works—and breaks down. Paul Thagard examines the dangers of misinformation on COVID-19, climate change, conspiracy theories, inequality, and the Russian invasion of Ukraine. He argues that effective responses to these problems require understanding how information is generated and s...
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
In recent years, artificial intelligence has increasingly been playing an essential role in diverse areas in medicine, assisting clinicians in patient management. In nephrology and transplantation, artificial intelligence can be utilized to enhance clinical care, such as through hemodialysis prescriptions and the follow-up of kidney transplant patients. Furthermore, there are rapidly expanding applications and validations of comprehensive, computerized medical records and related databases, including national registries, health insurance, and drug prescriptions. For this Special Issue, we made a call to action to stimulate researchers and clinicians to submit their invaluable works and present, here, a collection of articles covering original clinical research (single- or multi-center), database studies from registries, meta-analyses, and artificial intelligence research in nephrology including acute kidney injury, electrolytes and acid–base, chronic kidney disease, glomerular disease, dialysis, and transplantation that will provide additional knowledge and skills in the field of nephrology and transplantation toward improving patient outcomes.
Patient Blood Management (PBM) is an innovative clinical concept that aims to reduce the need for allogenic blood transfusions, cut health-care costs, and avert or correct the risk factors related to blood transfusion, thus minimizing the rate of side effects and complications. This comprehensive hands-on volume offers a three-point approach for the implementation of PBM to improve patient outcome, focusing on how to prevent or treat anemia, reduce blood loss, and increase anemia tolerance. The book also goes beyond preoperative PBM, with detailed accounts of coagulation disorder management and the administration of coagulation products and platelet concentrates. Special Features: Presents a...
This case report describes the poor outcome of a female patient who underwent elective nephrectomy. Unfortunately, the patient was suffering from undiagnosed preoperative platelet dysfunction and anemia, although blood count and clotting were almost within normal ranges two weeks earlier at the day of preoperative assessment for anesthesia. In this respect, intensive preoperative evaluation of the coagulation system embedded in a comprehensive patient blood management (PBM) concept might have the potential to detect preoperative coagulopathy and anemia and thereby could improve clinical outcome. About the Patient Blood Management Case Report Series Patient Blood Management (PBM) is a multidisciplinary, evidence-based approach to improve perioperative patient care. The concept includes preoperative screening, diagnosis and treatment of anemia and hemostasis, adequate blood product utilization and blood-sparing techniques. The use of a PBM concept will be of benefit for patients, society, doctors and hospitals. The case reports in this series will provide a case-based deeper understanding of the concept.
Die 5-bändige Buchreihe „AE-Manual der Endoprothetik“, herausgegeben von der Arbeitsgemeinschaft für Endoprothetik, bietet eine umfassende Darstellung der wissenschaftlichen Grundlagen und der klinischen Praxis des künstlichen Gelenkersatzes für die Gelenke Hüfte, Knie, Schulter, Ellenbogen, Sprunggelenk und Fuß. Parallel zu diesen gedruckten Werken erscheinen online Versionen, die als Live Reference-Ausgaben kontinuierlich aktualisiert werden. AE-Manual der Endoprothetik – Endoprothetik des Hüftgelenkes, 2. Auflage Komplett durch das Expertenteam Perka C, Heller KD, Rudert M und Morlock M überarbeitet und ins eReferenzwerk integriert wurde die Ausgabe „Hüfte“. Präsentiert wird der aktuelle Wissensstand rund um die Hüftendoprothetik in seiner ganzen Breite. Das Themenspektrum reicht von Anatomie und Kinematik über die verschiedenen Implantatsysteme und OP-Techniken bis zu Komplikationen und Revisionen.