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This best-selling resource explores the full spectrum of surgical techniques used in spine surgery, and describes how to avoid and manage complex problems. It emphasizes how to achieve successful outcomes and minimize risks. The 2nd Edition delivers more than 25 brand-new chapters, as well as extensive revisions and updates throughout, to reflect all of the latest advances in the field. It also features contributions from an increased number of orthopaedic surgeons to round out the strong coverage provided by the many neurosurgeon contributors. Features contributions from well-known neurosurgeons and orthopaedic surgeons, for well-rounded, authoritative coverage from beginning to end. Offers...
Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.
Volume 51 of Clinical Neurosurgery is the official compendium of the platform presentations at the 53rd Annual Meeting of the Congress of Neurological Surgeons held in October, 2003.
This practical, step-wise text covers the surgical approaches, resection strategies and reconstruction techniques used for each type of presenting tumor of the spine. Demonstrating the variety of anterior, posterior and intradural approaches and stabilization techniques, and spanning from pathologies of the craniocervical region to sacral and intradural pathologies, each chapter is generously illustrated with figures, radiographs and intraoperative photos. The chapters themselves follow a consistent and user-friendly format: the anatomy and biomechanics of a specific region, patient evaluation, essential oncologic principles, the decision-making process, and technical steps of surgery. A representative case illustration is provided at the conclusion of each chapter, exemplifying pertinent concepts described. Additionally, video segments accompany selected chapters, providing real-time illustration of surgical techniques. Technical and in-depth, yet highly accessible, Spinal Tumor Surgery: A Case-Based Approach is an essential resource for orthopedic spine surgeons, neurosurgeons, and surgical oncologists operating on tumors of the spine.
The first of the four volumes introduces approaches to the patient, radiology fundamentals, perioperative evaluation and treatment, and surgical exposures and positioning; and it covers oncology. The second volume covers vascular disease and malformations, and epilepsy; the third, functional neurosurgery, pain, and pediatric issues; and the fourth, the peripheral nerve, radiation therapy and radiosurgery, the spine, and trauma. Basic science, in most cases, is represented in its own chapter in each section, so as to make the rest of the section chapters more clinical in focus.
Explores the full spectrum of surgical techniques used in spine surgery, and describes how to avoid and manage complex problems. It emphasizes how to achieve successful outcomes and minimize risks. The 2nd Edition delivers more than 25 brand-new chapters, as well as extensive revisions and updates throughout, to reflect all of the latest advances in the field. It also features contributions from an increased number of orthopaedic surgeons to round out the strong coverage provided by the many neurosurgeon contributors.
The turbulent history of generic pharmaceuticals raises powerful questions about similarity and difference in modern medicine. Generic drugs are now familiar objects in clinics, drugstores, and households around the world. We like to think of these tablets, capsules, patches, and ointments as interchangeable with their brand-name counterparts: why pay more for the same? And yet they are not quite the same. They differ in price, in place of origin, in color, shape, and size, in the dyes, binders, fillers, and coatings used, and in a host of other ways. Claims of generic equivalence, as physician-historian Jeremy Greene reveals in this gripping narrative, are never based on being identical to ...
This book presents a focused, case-oriented approach to a specific disease entity: tumors located within the spinal canal. Each tumor type constitutes its own chapter and additional chapters focus on more novel trends in the field, such as radiosurgery and minimally invasive surgical techniques. In each chapter, the authors provide expert opinions on preoperative goals, intraoperative techniques and decision-making, and postoperative paradigms, including surveillance guidelines and thresholds for initiating adjuvant therapy. The management of intradural tumors has become increasingly interdisciplinary, and one of the major goals of this text is to familiarize the treating neurosurgeon with t...