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Solid State Characterization of Pharmaceuticals
The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanced, practical coverage with industrial relevance, it covers a range of key applications in the field. The following topics are included: Physical properties and processes Thermodynamics Intellectual guidance X-ray diffraction Spectroscopy Microscopy Particle sizing Mechanical properties Vapour sorption Thermal analysis & Calorimetry Polymorph prediction Form selection
Principles of Thermal Analysis and Calorimetry
The use of thermal and calorimetric methods has shown rapid growth over the past few decades, in an increasingly wide range of applications. The original text was published in 2001; since then there have been significant advances in various analytical techniques and their applications. This second edition supplies an up to date, concise and readable account of the principles, experimental apparatus and practical procedures used in thermal analysis and calorimetric methods of analysis. Written by experts in their field, brief accounts of the basic theory are reinforced with detailed technical advances and contemporary developments. Where appropriate, applications are used to highlight particular operating principles or methods of interpretation. As an important source of information for many levels of readership in a variety of areas, this book will be an aid for students and lecturers through to industrial and laboratory staff and consultants.
Plant Tissue Culture Engineering
It is my privilege to contribute the foreword for this unique volume entitled: “Plant Tissue Culture Engineering,” edited by S. Dutta Gupta and Y. Ibaraki. While there have been a number of volumes published regarding the basic methods and applications of plant tissue and cell culture technologies, and even considerable attention provided to bioreactor design, relatively little attention has been afforded to the engineering principles that have emerged as critical contributions to the commercial applications of plant biotechnologies. This volume, “Plant Tissue Culture Engineering,” signals a turning point: the recognition that this specialized field of plant science must be integrate...
Computer Graphics in Biology
Computer graphics is being used to an increasing extent in the biological disciplines. As hardware costs drop and technological developments intro duce new graphics possibilities, researchers and teachers alike are becoming aware of the value of visual display methods. In this book we introduce the basics of computer graphics from the standpoints of both hardware and software, and review the main areas within biology to which computer graphics have been applied. The com puter graphics literature is vast, and we have not been able to give a full course on graphics techniques in these pages. We have instead tried to give a fairly balanced account of the use of graphics in biology, suitable for...
Structure and Function of the Neural Cell Adhesion Molecule NCAM
This book describes recent developments concerning structural, functional and possible therapeutic aspects of one particular CAM, the neural cell adhesion molecule (NCAM).
Central Regulation of Autonomic Functions
Central autonomic circuits in the brain and spinal cord are essential to vertebrate life because they are involved in controlling all basic bodily functions, including blood pressure, feeding, body temperature regulation voiding and reproduction. This wide-ranging text emphasizes the extraordinary advances that have been made over the last 20 years in understanding how the central nervous system controls autonomic functions.
Assessment of Polymeric Materials for Biomedical Applications
This book initiates with an introduction to polymeric materials, followed by various classifications and properties of polymeric implant material including various development methods of polymeric materials and their characterization techniques. An overview of various toxicology assessments of polymeric materials and polymeric materials for drug delivery system is also included. Design and analysis of polymeric materials-based components using Ansys software along with polymeric materials for additively manufactured artificial organs are also discussed. Features: Addresses assessment of polymeric materials in biomedical sciences, including classification, properties, and development of polym...
Physical Chemistry Research for Engineering and Applied Sciences - Three Volume Set
This 3-volume set covers new research and applications on physical chemical for engineering and applied sciences. Volume 1 discusses the principles and technological implications of industrial chemistry and biochemical physics. Volume 2 presents some fascinating phenomena associated with the remarkable features of high performance polymers and also
Pain
Pain integrates biology and psychology to study, as its central focus, the roots of pain in the nervous system and how pain is treated. It includes an account of placebos and cognitive therapies, the harmful effect of the patient making catastropic interpretations, and the pain of social rejection.
Smell and Taste
Smell and Taste, Volume 164 focuses on recent clinical research regarding two of our primary chemical senses, smell and taste. This volume is the most comprehensive neurology book on disorders of smell and taste function. Its major sections include epidemiology, anatomy and physiology, and clinical assessment, including neuroimaging, clinical conditions affecting smell and taste function (e.g., autoimmune disorders, head trauma, diseases of the nose and mouth, etc.). The widespread use of olfactory testing in clinical trials searching for biomarkers of neurodegenerative diseases is reviewed, along with evidence that smell dysfunction can be an early marker in neurodegenerative diseases and autoimmune disorders. - Covers all aspects of disorders of taste and smell for beginning students of various disciplines (neurology, psychiatry, neuropsychology, otolaryngology) - Teaches that smell and taste testing can be useful in differential diagnosis and can assess brain regions not normally assessed by traditional neurological or neuropsychological tests - Addresses, in detail, recent evidence that smell loss is a better predictor of future mortality than dementia and even heart disease
