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Mania
Since the 1990 publication of Goodwin and Jamison's classic text on mania and bipolar and unipolar depression, Manic-Depressive Illness, there have been a number of significant advances in the research, diagnosis, and treatment of mania and bipolar disorder. Developed and written by experts at the forefront of these advances, Mania: Clinical and Research Perspectives provides a comprehensive overview of all recent developments on all aspects of mania. Mania is divided into three sections: diagnostic considerations, biological aspects, and treatment. "Diagnostic Considerations" includes coverage of the diagnostic revisions in DSM-IV, special comorbidity issues in children and substance abuse,...
Predictors of Treatment Response in Mood Disorders
Predictors of Treatment Response in Mood Disorders is the first text devoted solely to predicting responses to treatment in mood disorders. This concise, practical guide to clinical and biological factors affecting mood disorders will help clinicians and managed care administrators assign the correct somatic therapy -- the first time. In this day of increasingly scrutinized health care costs, it makes sense to examine all avenues of knowledge in predicting treatment response in mood disorders. Practical clinical examples from the chapter authors investigate questions such as, Which antidepressant should be used for atypical or bipolar depression? When should anticonvulsants be chosen over lithium? Does the DST or any blood test help in choosing medications? Chapters cover antidepressants (tricyclics, monoamine oxidase inhibitors, and SSRIs), mania treatments (lithium, carbamazepine, valproate, and neuroleptics), electroconvulsive therapy, and future treatment issues.
Chronic Fatigue and Related Immune Deficiency Syndromes
The latest research in neurobiology and in biological psychiatry has led to the discovery of many interactions between mood states and alterations in brain neurochemistry, neuroendocrinology, and brain imaging. Chronic Fatigue and Related Immune Deficiency Syndromes presents a state-of-the-art synthesis of research into disorders of chronic fatigue. It examines the relationship of chronic fatigue and related immune deficiency syndromes to major biological depression and reviews how they are alike and how they differ in etiology, psychopathology, neuroendocrinology, neurochemistry, and treatment. The chapters on treatment review all the varying approaches currently being used (along with the theories on which they are based) to set the scene for future developments in antivirals and antidepressants. This comprehensive yet concise text presents what is known on chronic fatigue syndrome from the vantage point of experts in the fields of immunology, virology, and neuroendocrinology.
Alterations of Metabolites in the Nervous System
In neurosciences one may say, '"All roads lead to Rome. " It seems as though wherever one starts, the course of investigation leads to the same major ques tions about nervous system function and dysfunction. In thinking about what to write in this preface, it occurred to me that it might be best to deal with that with which I am most familiar and to trace to some extent my own '"road to Rome. '' As I look over my work of the last 37 years, it becomes clear to me that it can be epitomized as a search for patterns. What usually began as a single minded devotion to in-depth analysis of one or a small number of variables always has led to questions of how the results might relate to the whole li...
Neurobiology of Cerebrospinal Fluid 2
Since the publication of Neurobiology of Cerebrospinal Fluid 1 in 1980, that text has become the definitive reference concerning cerebrospinal fluid (CSF) for both basic scientists and clinicians involved in the investigation of degenerative, convulsive, cerebrovascular, traumatic, immunological, demyelinating, inflammatory, neoplastic, neuroendocrine, and psychiatric disorders. That initial volume began a tradition of detailed topic reviews written by international authorities with first-hand expertise in their respective fields of CSF research. Neurobiology of Cerebrospinal Fluid 2 represents a hefty collection of extensively refer enced and illustrated chapters covering topics not discuss...
New Directions in Affective Disorders
This book is presented as a 1989 update on the task set by Robert Burton in his "Anatomy ofMelancholy," published in 1621. Burton's treatise addressed ques tions regarding depression which are still highly relevant today: ." . . What is it, with all the kinds, causes, symptoms, prognostickes and several cures ofit. . . . " These remain the core issues in affective disorders notwithstanding the remarkable progress that has been made in addressing them. New Directions in Affective Disorders sets out to provide an overviewofwhat has been achieved with particular emphasison developing trends and novel initiatives in bothfundamental research and treatment. The overriding objective of the book is ...
The Postpartum Effect
The past decade has seen strides in the diagnosis and treatment of postpartum depression, which affects 400,000 women annually in the United States. Yet the most tragic of these cases—the filicides and suicides that spark tabloid frenzy—continue to be horribly misdiagnosed. Dr. Arlene Huysman, drawing on decades of clinical work, here describes the postpartum effect, the missing key to treatment. Dr. Huysman’s book is designed to educate the general public, and to serve as a tool in the care provider’s hands. In The Postpartum Effect the author records anonymous first-person testimonies from mothers who were tempted to harm their children. She constructs a profile of mothers at greatest risk of the disease. All leading up to the central question: What drives a mother to the ultimate travesty? Dr. Huysman’s measured, empirical approach is a plea for understanding.
