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Principles of Evolutionary Medicine
A new updated edition of the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.
Fat, Fate, and Disease
'Why are we losing the war against obesity and chronic disease?' This is the simple question Peter Gluckman and Mark Hanson ask, exploring the dominant myth that the exploding epidemic of obesity, heart disease, and diabetes can be tackled by focusing on adult life styles. Addressing the flawed approach of the weight-loss industry, they explain why a continued focus simply on diet and exercise will fail. Highlighting the implications of the growing burden of these problems in the developing world, they show that the scientific enterprise ignores the reality of the social, cultural, and biological determinants that make different populations and people respond differently to living in the mod...
Developmental Origins of Health and Disease
This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound consequences for adult health and diseases. Although the epidemiological evidence for this link has long proved compelling, it is only much more recently that the scientific and physiological basis has begun to be studied in depth and fully understood. The compilation, written by many of the world's leading experts in this exciting field, summarizes these scientific and clinical advances.
Plasticity, Robustness, Development and Evolution
How do we understand and explain the apparent dichotomy between plasticity and robustness in the context of development? Can we identify these complex processes without resorting to 'either/or' solutions? Written by two leaders in the field, this is the first book to fully unravel the complexity of the subject, explaining that the epigenetic processes generating plasticity and robustness are in fact deeply intertwined. It identifies the different mechanisms that generate robustness and the various forms of plasticity, before considering the functional significance of the integrated mechanisms and how the component processes might have evolved. Finally, it highlights the ways in which epigenetic mechanisms could be instrumental in driving evolutionary change. Essential reading for biologists and psychologists interested in epigenetics and evolution, this book is also a valuable resource for biological anthropologists, sociobiologists, child psychologists and paediatricians.
Ingenious
As humans evolved, we developed technologies to modify our environment, yet these innovations are increasingly affecting our behavior, biology, and society. Now we must figure out how to function in the world we’ve created. Over thousands of years, humans have invented ingenious ways to gain mastery over our environment. The ability to communicate, accumulate knowledge collectively, and build on previous innovations has enabled us to change nature. Innovation has allowed us to thrive. The trouble with innovation is that we can seldom go back and undo it. We invent, embrace, and exploit new technologies to modify our environment. Then we modify those technologies to cope with the resulting ...
Mismatch
We have built a world that no longer fits our bodies. Our genes - selected through our evolution - and the many processes by which our development is tuned within the womb, limit our capacity to adapt to the modern urban lifestyle. There is a mismatch. We are seeing the impact of this mismatch in the explosion of diabetes, heart disease and obesity. But it also has consequences in earlier puberty and old age. Bringing together the latest scientific research in evolutionary biology, development, medicine, anthropology and ecology, Peter Gluckman and Mark Hanson, both leading medical scientists, argue that many of our problems as modern-day humans can be understood in terms of this fundamental and growing mismatch. It is an insight that we ignore at our peril.
Nutrition and Lifestyle for Pregnancy and Breastfeeding
Explaining the practical implications of new discoveries in 'life-course biology', Nutrition and Lifestyle for Pregnancy and Breastfeeding is an informed resource on factors that affect offspring development. The impact of parental lifestyle and behavioural choices influence not only fetal development and birth outcomes, but also postnatal development, yet guidance on appropriate diet, behaviour, and exposures during pregnancy is often confusing and contradictory. With accessible explanations of the latest scientific research, and clear summaries and recommendations, this book is a valuable and authoritative guide for all levels of health care providers. The authors provide an overview of th...
The Fetal Matrix: Evolution, Development and Disease
New discoveries reveal how crucial interactions which determine our destiny occur before birth, when our genes interact with their environment as the embryo and fetus develop. These processes - in the matrix of the womb - are evolutionary echoes of mechanisms which allowed our hunter-gatherer ancestors to survive. These exciting insights into predictive adaptive responses suggest new ways of protecting the health of the fetus, infant and adult. If inappropriate they can trigger obesity, diabetes and heart disease, formerly thought to result solely from adult lifestyle. The new concepts in this book are crucial to understanding the daunting public health burden in societies undergoing rapid transition from poverty to affluence. They add an important new dimension to evolutionary theory. Synthesising developmental biology, evolutionary history, medical science, public health and social policy, this is a ground-breaking and fascinating account by two of the world's leading pioneers in this important emerging field.
Nutrigenomics and Proteomics in Health and Disease
Now in a revised second edition, Nutrigenomics and Proteomics in Health and Disease brings together the very latest science based upon nutrigenomics and proteomics in food and health. Coverage includes many important nutraceuticals and their impact on gene interaction and health. Authored by an international team of multidisciplinary researchers, this book acquaints food and nutrition professionals with these new fields of nutrition research and conveys the state of the science to date. Thoroughly updated to reflect the most current developments in the field, the second edition includes six new chapters covering gut health and the personal microbiome; gut microbe-derived bioactive metabolite...
Science Diplomacy: New Day Or False Dawn?
As modern foreign policy and international relations encompass more and more scientific issues, we are moving towards a new type of diplomacy, known as “Science Diplomacy”. Will this new diplomacy of the 21st century prove to be more effective than past diplomacy for the big issues facing the world, such as climate change, food and water insecurity, diminishing biodiversity, pandemic disease, public health, genomics or environmental collapse, mineral exploitation, health and international scientific endeavours such as those in the space and the Antarctic?Providing a new area of academic focus that has only gathered momentum in the last few years, this book considers these questions by br...
