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The Kinetochore:
Kinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s. “The Kinetochore: from Molecular Discoveries to Cancer Therapy” presents a thorough up-to-date analysis of kinetochore and centromere composition, formation, regulation, and activity, both in mitosis and meiosis, in humans and “model” eukaryotic species, and at natural and mutant neocentromeres. Recently initiated translational research on kinetochores is also discussed as kinetochores are being mined as a very rich target for the next generations of anti-cancer drugs.
Peter de Rivo on Chronology and the Calendar
Critical edition of previously unpublished works by a key philosopher of the fifteenth-century Low Countries Peter de Rivo (c.1420–1499), a renowned philosopher active at the University of Leuven, is today mostly remembered for his controversial role in the quarrel over future contingents (1465–1475). Much less known are his contributions to historical chronology, in particular his attempts to determine the dates of Christ’s birth and death. In 1471, Peter made an original contribution to this long-standing discussion with his Dyalogus de temporibus Christi, which reconciles conflicting views by rewriting the history of the Jewish and Christian calendars. Later in his career, Peter tackled the issue of calendar reform in his Reformacio kalendarii Romani (1488) and engaged in a heated debate with Paul of Middelburg on the chronology of Christ. This book edits the Dyalogus and Reformacio and sets out their context and transmission in an extensive historical introduction.
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Individuation in Scholasticism
Examines the place of individuation in the work of over 25 scholastic writers from when Arabic and Greek thought began to impact Europe, until scholasticism died out. Experts on particular authors contribute chapters that cover all the major figures and a representative few of the lesser. Other chapters survey the problem of individuation, the medieval legacy, Islamic and Jewish thought, and the continuing scholastic influence on modern philosophy. Annotation copyright by Book News, Inc., Portland, OR
Informationsintegration in mehrsprachigen Textchats
Die vorliegende Arbeit widmet sich der Informationsintegration in maschinell übersetzten, mehrsprachigen Textchats am Beispiel des Skype Translators im Sprachenpaar Katalanisch-Deutsch. Der Untersuchung von Textchats dieser Konfiguration wurde sich bislang nur wenig zugewendet. Deshalb wird der zunächst grundlegend explorativ ausgerichteten Forschungsfrage nachgegangen, wie Personen eine maschinell übersetzte Textchat-Kommunikation wahrnehmen, wenn sie nicht der Sprache des Gegenübers mächtig sind. Damit einher geht auch die Untersuchung der Informationsextraktion und -verarbeitung zwischen Nachrichten, die in der eigenen Sprache verfasst wurden, und der Ausgabe der Maschinellen Überse...
The Kinetochore:
Kinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s. “The Kinetochore: from Molecular Discoveries to Cancer Therapy” presents a thorough up-to-date analysis of kinetochore and centromere composition, formation, regulation, and activity, both in mitosis and meiosis, in humans and “model” eukaryotic species, and at natural and mutant neocentromeres. Recently initiated translational research on kinetochores is also discussed as kinetochores are being mined as a very rich target for the next generations of anti-cancer drugs.
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