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Areas addressed in this excellent text include the overall response of the endothelium to hemodynamic forces, and molecular biology with gene regulation taking a central role.
Stem cells, tissue engineering and regenerative medicine are fast moving fields with vastly transformative implications for the future of health care and capital markets. This book will show the state of the art in the translational fields of stem cell biology, tissue engineering and regenerative medicine. The state of developments in specific organ systems, where novel solutions to organ failure are badly needed such as the lungs, kidney and so forth, are discussed in various chapters. These present and future advances are placed in the context of the overall field, offering a comprehensive and quick up-to-date drink from the fountain of knowledge in this rapidly emerging field.This book provides an investigator-level overview of the current field accessible to the educated scientific generalist as well as a college educated readership, undergraduates and science writers, educators and professionals of all kinds.
The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.
The potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. In this book, many of the most prominent researchers discuss the challenging topics of stem cell engineering, for example: Ethical issues of stem cell research; technological challenges, stem cell growth and differentiation, therapeutic applications, bioreactors and bioprocesses, high throughput and microfluidic screening platforms, stem cell identification and sorting, intercellular signaling and engineered niches, novel approaches for embryonic and adult stem cell growth and differentiation, stem cells and drug discovery, screening platforms. Stem Cell Engineering offers valuable background and reference for both the public and professionals including industrial staffers, faculty, researchers, engineers, students and scientific journalists.
The papers contained in this book were presented at a NATO Advanced Research Workshop (ARW) held at Cape Sounion, Athens, Greece, 19-24 May, 1991. The twenty-eight more comprehensive papers represent the key subjects of the ARW covered by invited speakers. The thirty-four short papers pre sented in a research format are contributions of those invited to participate in the ARW. There was a total of 70 participants from 21 countries. The objectives of the ARW were as follows: to review current knowledge of biological control of plant diseases and plant parasitic nematodes, with emphasis on mechanisms at the molecular, cellular, organismal, and ecosystem level; to examine and expand on current concepts and synthesize new concepts; to identify and prioritize limitations in the use of biological control for plant diseases and nematodes and the scientific research needed to overcome these limitations; and to develop strategies for biological control through management of resident agents or introduction of natural or modified agents.
Step-by-step, practical guidance for the acquisition, manipulation,and use of cell sources for tissue engineering Tissue engineering is a multidisciplinary field incorporatingthe principles of biology, chemistry, engineering, and medicine tocreate biological substitutes of native tissues for scientificresearch or clinical use. Specific applications of this technologyinclude studies of tissue development and function, investigatingdrug response, and tissue repair and replacement. This area israpidly becoming one of the most promising treatment options forpatients suffering from tissue failure. Written by leading experts in the field, Culture of Cellsfor Tissue Engineering offers step-by-step,...
First multi-year cumulation covers six years: 1965-70.
From the 19-29 May 1991 the NATO ASI Course PAsthma Treatment: A P Multidisciplinary Approach was held in Erice, on the rocky North West Coast of Sicily, facing the ancient Phoenician shore of the African Continent. Sixty NATO sponsored participants arriving from many different European Countries - Nato members and non - attended the course. Qualified researchers from Europe and the United States held extensive lectures, short meetings and small informal group discussions. Erice is a magical place which draws together people from different backgrounds and cultures under her Mediterrean charm, recreating the ancient Greek openair discussion atmosphere. And so, during the 10 days gathering, th...
There has been an explosion of research activity related to angiogenesis in recent years, and hundreds of laboratories worldwide are actively involved in many aspects of angiogenesiS. The literature on angiogenesis increases exponentially every year, and more than 16,000 peer-reviewed articles have been published the past 25 years, which are scattered in basic science and clinical journals. The complexity of the cascade of events leading to new vessel formation from preexisting ones has challenged scientists in cell biology, biochemistry, physiology, pharmacology, molecular biology, developmental biology, and other fields. With their multidisciplinary approach and the powerful new techniques...
This volume contains the proceedings of the NATO Advanced Study Institute held in Porto Conte (Alghero), Sardinia, September 15-27, 1991. The A. S. 1. was attended by 86 graduate and postgraduate students from 18 different countries, and was hosted by the newly founded International Laboratory of Molecular Genetics of Porto Conte, directed by Prof. Marcello Siniscalco. The A. S. I. was funded by NATO Scientific Affairs Division, the International Union of Immunological Societies, the European Community (Directorate General for Science, Research and Development), the Italian Research Council, and the San Raffaele Institute of Milano. In addition, a number of students who reside in the U. S. received travel funds from the U. S. National Science Foundation, and the Turkish National Fund provided financial assistance to several students from Turkey. When we decided to organize a course on T lymphocytes, our concern was to reach a balance between the teaching of both the hard core principles and the latest experimental findings of cellular immunology, and the recently expanded interfaces with the not-yet known: hypotheses, speCUlations, new projections to be born from the discussions.