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Calcium signalling
The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells. The focus within these methods in on the broad range of fluorescence imaging technology, in particular on optical sectioning techniques and fast image acquisition. In addition to these general guidelines there are application examples in a context beyond calcium signalling in two major fields: investigations of isolated cardiac myocytes and red blood cell related research. While the cellular cardiology section provides snapshots of certain calcium signalling aspects, the red blood cell part presents an overview from the functional identification of calcium-channels to a concept of physiological and pathophysiological relevance.
Animal-friendly methods for rodent behavioral testing in neuroscience research
Rodent behavioral testing has been used to study brain functions since the 1890s and has become a gold-standard model in modern neuroscience. Up to the 1950s, most behavioral tests on laboratory rodent models were based on punishments and rewards. Both approaches can lead to a certain degree of animal pain or suffering. Punishments involved the employment of painful stimuli, typically electric shocks. Passive avoidance and fear conditioning tests, among the most widely used behavioral paradigms used to evaluate learning and memory in rodents, can be performed using only a single brief shock. Other tests, such as the active avoidance, might require up to tens or hundreds of shocks, strongly c...
Trusted Computing - Challenges and Applications
This book constitutes the thoroughly refereed post-conference proceedings of the First International Conference on Trusted Computing and Trust in Information Technologies, TRUST 2008, held in Villach, Austria, in March 2008. The 13 revised full papers presented together with 1 invited lecture were carefully reviewed and selected from 43 submissions. The papers cover the core issues of trust in IT systems and present recent leading edge developments in the field of trusted infrastructure and computing to foster the international knowledge exchange necessary to catch up with the latest trends in science and technology developments.
Cancer Investigation
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Catalogue of the Library of the Mercantile Library Association of San Francisco
Reprint of the original, first published in 1874. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
