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The only comprehensive overview of the molecular basis and clinical features of the genetic disorder tuberous sclerosis, which affects approximately 50,000 people in the US alone. Special focus is placed on novel insights into the signal transduction pathways affected by the disease as well as genotype phenotype correlations, while existing and potential therapies are also discussed in depth. The editors are leading experts in research and treatment of the disease as well as the Vice President of the Tuberous Sclerosis Alliance, the only voluntary health organization for TSC in the US.
Chromovitrectomy is a novel approach to visualize the vitreous or retinal surface during vitreoretinal surgery. In recent years, the widely used indocyanine green (ICG) has made the surgical maneuver of inner limiting membrane peeling tremendously safer and efficient. Also, numerous dyes have been applied in experimental settings with promising or devastating results. This volume highlights the major clinical and experimental results of currently used novel vital dyes. The first chapters describe the transparent structure of the vitreous body and summarize historical considerations to visualize its structure by optical coherence tomography, dye injections or autologous cells during surgery a...
Written by internationally renowned experts, Clinical Ophthalmic Oncology provides practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. The book supplies all of the state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible. Using the information provided, readers will be able to provide effective patient care using the latest knowledge on all aspects of ophthalmic oncology, to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs, and to locate required information quickly owing to the clinically focused and user-friendly format. In this volume guidance is provided on diagnosis and therapy for retinal tumors including vitreoretinal lymphoma and paraneoplastic disorders.
Macular Surgery, Second Edition serves as a comprehensive and contemporary review of macular diseases and their management. An exhaustive review of the latest proven surgical techniques and therapies for treatment of macular disorders is provided, with emphasis on proven techniques from extensive reviews of controlled clinical trials. Specific chapters of the book are devoted to age-related macular degeneration, diabetic retinopathy, macular holes, epiretinal membranes, subretinal hemorrhage, and choroidal neovascularization. An entire section is devoted to prevention of complications from macular surgery. All chapters are written by leading experts within the field.
Vol. 174AX bound with Proceedings of the Ocean Drilling Program. Scientific results Vol. 174A.
Fundus Fluorescein and Indocyanine Green Angiography: A Textbook and Atlas is a complete and detailed reference that comprehensively covers fluorescein angiography, the more recent and advancing indocyanine green angiography and their effectiveness in identifying and evaluating various retinal diseases. Prof. Amar Agarwal has teamed up with more than 30 retina specialists to provide eyecare professionals with the most current and essential information for the successful employment and accurate interpretation of these vital diagnostic tests. Sections inside the book include: - Basics and principles - Macular diseases - Vascular retinal diseases - Non vascular retinal diseases - Optic nerve di...
This pioneering work presents the first comprehensive economic history of medieval Denmark. It puts data produced by more than a century of historical research into a new context and includes a multitude of information based on primary research. The book abounds in knowledge of natural and human resources, rural life, urban industries, tax and commodity trade. Arguing that the development of the Danish resources from the eleventh to the middle of the fourteenth century cannot be viewed simply as a period of prosperity, and conversely that the Late Middle Ages were characterized as much by growth as by recession, the book places itself in an international historiographical controversy. The Danish Resources will become an indispensable standard work for students of Danish and north European medieval history.
Danish director Lars von Trier has produced more than 20 films since his first appearance with The Elements of Crime in 1984. One of the most acknowledged - and most controversial - film directors of our time, Trier's films often escape the representational production of meaning. In Lars von Trier's Renewal of Film 1984-2014. Signal, Pixel, Diagram scholar Bodil Marie Stavning Thomsen offers a comprehensive discussion of Lars von Trier's collected works. Examining Trier's experiments with narrative forms, genre, camera usage, light, and colour tones, she shows how Trier's unique ethically involving style activates the viewer's entire perception apparatus. In understanding this affective involvement, the author frames the discussion around concepts from Gilles Deleuze, Alois Riegl, Brian Massumi and others on the haptic image, the diagram, affect and the signaletic material.