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Insights in Thalassemia: From Genomics to Clinical Practice
IN LOVING MEMORY of Dr. Zarina Abdul Latiff. Thalassemia is a genetically heterogenous group of hemoglobinopathy disorders, characterised by imbalanced production of the α-globin or β-globin subunits of hemoglobin. Although the causative genotype is a key determinant of disease severity, the clinical spectrum and phenotype are affected by secondary and tertiary genetic modifiers. The public health and clinical burden of the disease is apparent with 1.5% of the global population being carriers and an estimated 400,000 affected births annually, with the majority in lower-middle-income countries. Although diagnostics and clinical management have evolved over the last decade, there is still much to be addressed in terms prevention, utility of molecular diagnostics, treatment outcome and quality of life.
Artificial Neural Networks and Machine Learning – ICANN 2016
The two volume set, LNCS 9886 + 9887, constitutes the proceedings of the 25th International Conference on Artificial Neural Networks, ICANN 2016, held in Barcelona, Spain, in September 2016. The 121 full papers included in this volume were carefully reviewed and selected from 227 submissions. They were organized in topical sections named: from neurons to networks; networks and dynamics; higher nervous functions; neuronal hardware; learning foundations; deep learning; classifications and forecasting; and recognition and navigation. There are 47 short paper abstracts that are included in the back matter of the volume.
Thalassemia, An Issue of Hematology/Oncology Clinics of North America, E-Book
In this issue of Hematology/Oncology Clinics, guest editors Drs. Edward J. Benz, Jr. and Vijay G. Sankaran bring their considerable expertise to the topic of Thalassemia. Top experts in the field provide an overview of the history, epidemiology, pathogenic mechanisms, and clinical management of the thalassemia syndromes. - Contains 16 practice-oriented topics including molecular basis and genetic modifiers of thalassemia; fetal hemoglobin in thalassemia; clinical complications and their management; iron chelation in thalassemia; fertility and pregnancy in women with transfusion-dependent thalassemia; gene therapy and genome editing in thalassemia; emerging medical therapies for thalassemia; and more. - Provides in-depth clinical reviews on thalassemia, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Eu Institutions Register
Details of over 5,900 key personnel in each of the major institutions, including: European Commission, European Parliament, Economic and Social Committee, Council of the European Union, Court of Justice, European Investment Bank, Court of Auditors, Committee of Regions and EU Agencies.
Artificial Neural Networks and Machine Learning – ICANN 2016
The two volume set, LNCS 9886 + 9887, constitutes the proceedings of the 25th International Conference on Artificial Neural Networks, ICANN 2016, held in Barcelona, Spain, in September 2016. The 121 full papers included in this volume were carefully reviewed and selected from 227 submissions. They were organized in topical sections named: from neurons to networks; networks and dynamics; higher nervous functions; neuronal hardware; learning foundations; deep learning; classifications and forecasting; and recognition and navigation. There are 47 short paper abstracts that are included in the back matter of the volume.
The Thalassaemia Syndromes
In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in the laboratory or clinical setting, particularly in areas where thalassaemia is common either in the native population or in immigrant communities. The fourth edition has been both updated and re-organized. Three new chapters have been added on the link between alpha-thalassaemia and mental retardation, on avoidance and population control and on global epidemiology. Considerable emphasis is placed on molecular pathology reflecting the huge burst of information to have come out of this field in the last few years.
The 1906 Olympic Games
One of the early concepts of the Olympic Games was to include "intercalated" Games every four years between the normal cycle, and to hold these Games in Athens, the ancestral home of the Olympics. In 1906 the first, and only one, of these games was held. Occurring only two years after the St. Louis Games of 1904 and two years before the London Games of 1908, the Athens Games were considered by many not to be "official"; social and political forces prevented continuation of the intercalation cycle in 1910 and later. Yet these Games were surprisingly successful and helped guarantee the survival of the modern Olympics. This book, fourth in the series on the early Olympics, presents all the data on 29 nation and city-state participants in more than a dozen events in the Athens Games. Scores and descriptions are provided, and many historical errors and omissions in other sources are corrected. Appendices include the published program for the Games, the actual schedule followed during the Games, and country-by country listings of all participating athletes.
Disorders of Hemoglobin
Completely revised new edition of the definitive reference on disorders of hemoglobin.
Ranking of researchers and scientists in Greece in 2017 according to Google Scholar database
Scope: The classification of researchers and scientists in Greece in a unified list based on the citation impact and dissemination level of their scientific work according to Google Scholar database. Classification criteria: First criterion is h-index. In the case of equal h-index, the following scientometric indicators are used for the classification. The number of total citations, the i10-index, the total impact factor of scientist, the m-index or m-quotient of scientist. Information resource: The h-index, citations and i10-index derived from the public profiles of researchers in the Google Scholar database. In addition, the calculation of total impact factor and m-index of each researcher...
Diaspora Merchants in the Black Sea
Presented here for the first time in English, this richly detailed study--based on British, French, Greek, and Russian archival sources--tells the story of the powerful Greek trading houses that competed successfully with North America to feed the industrializing population of Western Europe. Vassilis Kardasis presents this commercial history by charting the rise of Greek merchant houses to a position of dominance over the export of trade in Russian grain. Though the Greeks would eventually cede their dominance to the competition of cheaper American grain in the second half of the nineteenth century, their influence was felt in the transformation of Southern Russia to productive agricultural land and the formation of large Black Sea port cities which would eventually encourage massive immigration. Diaspora Merchants in the Black Sea fills an important gap in our understanding of the role of the diasporic Greek community in southern Russian history, the history of Greek maritime activity, and ultimately the history of economic relations between Eastern and Western Europe.
