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This book is unique in providing pertinent information on the various established roles carbohydrate play in the immune system and how the innate and adaptive immune systems respond to this type of microbial antigens. The editors selected only topics that have established basic and clinical relevance to this field. The topics from basic research are organised like a textbook, in order to guide the readers through complex sets of events that lead to clearance of or to immune responses toward carbohydrate antigens. The book is clear, concise and contains fully annotated summaries of the key basic and practical information on carbohydrate immunology from current literature. These topics are wri...
We are celebrating this year the hundred years ́ anniversary of allergen-specific immunotherapy. In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin” by administering increasing doses of grass pollen extract before the grass pollen season to allergic patients. Although it was unknown at that time that allergy represents an immunological hypersensitivity disease, the treatment was effective and many observations made by Noon remained valid until today. Today allergen-specific immunotherapy is well established as the only allergen-specific and disease-modifying treatment for IgE-mediated allergies and has long-lasting effects. In fact, more than 25% of the population suffer from IgE-mediated allergies which therefore represent a major health burden of our society, particularly because untreated allergy often progresses to severe disabling forms of disease, such as asthma and sometimes kills sensitized people through anaphylaxis.
Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations. - Contributions from leading international authorities in the field - Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system - Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator
This monograph contains the proceedings of a conference devoted to progress and emerging issues in therapeutic cancer vaccine development since the 1998 FDA/NCI workshop. The emphasis is on progress in the clinical trials of cancer vaccines in late-stage development, but the volume also includes presentations and discussions on exciting earlier-stage products as well as updates on regulatory positions in the USA, Canada, Europe, and Australia. Session I concentrates on regulatory considerations in cancer vaccine development, including a round table of regulatory agency representatives from North America, Europe, and Australia. Session II continues with a consideration of several different types of cancer vaccines, including whole cells, cell lysates, multivalent recombinants and peptides. Session III highlights dendritic cell vaccines and dendritic cells fused to tumour cell vaccines. Session IV focuses on preventive cancer vaccines for cervical carcinoma and liver cancer and various aspects of the immune response to cancer vaccines.
Melanomas: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Melanomas: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Melanomas: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
This collection aims to explore the transformative potential of computer vision and artificial intelligence (AI) in revolutionizing medical imaging. Medical imaging is still in a state of infancy. The interpretation of medical images is often time-consuming and subject to human error. By leveraging computer vision algorithms and AI technologies, medical imaging can be enhanced with automated analysis, pattern recognition, and predictive modelling, leading to improved accuracy, speed, and clinical outcomes. This collection provides an overview of the current state, challenges, and prospects of integrating computer vision and AI techniques into existing medical imaging technologies. Medical imaging has the potential to create a paradigm shift in healthcare in future enhancing diagnostic accuracy, personalised treatment, and overall patient care. While challenges related to data quality, interpretability, and ethics must be navigated, the future for AI based imaging technology is bright.