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Employing a multidisciplinary approach to phospholipid research, this work catalogues the current knowledge of this class of molecules and details the general, chemical, physical and structural properties of phospholipid monolayers and bilayers. Phospholipid applications are also covered.
The book discusses the essential chemistry of phospholipids along with an account of the metabolism. The phospholipases and phospholipase A2 is explained since its structure and the mechanism of its action have been investigated in greater detail than any other phospholipid metabolising enzyme. The increasingly important topic of phospholipid exchange proteins is also treated. Furthermore, since the use of biochemically defined mutants shows great promise for the better understanding of phospholipid biosynthesis and function, the book also discusses genetic control of the enzymes involved.
Phospholipid technology and applications is an essential reference for technologists developing food and cosmetics products, scientists researching phospholipids in biological and food systems, technologists in fats and oils refining, and scientists developing drugs and drug delivery systems and carriers. The major source of phospholipids is the lecithin recovered during degumming of vegetable oils, particularly soybean oil. This crude material finds uses in its own right but can be purified through a series of processes which eventually lead to individual phospholipid classes such as phosphatidylcholines. It is widely accepted that oil and water do not mix but there are several areas in sci...
Employing a multidisciplinary approach to phospholipid research, this work catalogues the current knowledge of this class of molecules and details the general, chemical, physical and structural properties of phospholipid monolayers and bilayers. Phospholipid applications are also covered.
"A Guide to Phospholipid Chemistry" provides an introduction to phospholipid chemistry for graduate students and practicing research scientists who are encountering these compounds for the first time. Hanahan describes the methodology for recovering lipids intact from cells or tissues and emphasis is placed on the analytical methodology for assay of phospholipids, together with a detailed description of the routes to their proof of structure. Written in a simple and straightforward manner with several "hands-on" examples that can be followed easily in any laboratory, this book will be beneficial not only to professionals but to graduate students as well.
This book provides a concise introduction to phospholipid chemistry and is intended for a broad audience of biologists, biochemists, and graduate students. Developed as part of a graduate course on lipids, this book also serves as a reference for laboratory investigators on signal transduction and biological membranes. The first part of the text is devoted to an orientation to the chemical nature of lipids in general, how they are thought to be associated in the cell, and the methodology by which the cellular lipids (including the phospholipids) can be recovered from cells and subjected to an initial identification. Subsequent chapters characterize the choline-containing phospholipids, inclu...
Phospholipids are no longer considered exclusively as the building blocks of biomembranes, but are now regarded to be exceptionally important to cellular signalling.Another conclusion resulting from studies over the past several years is that no single general scheme for the role of phospholipids during cell activation can be drawn as representative of all cells. This book presents a comprehensive view of the recent advances made in certain major research areas within the field of phospholipid metabolism in cellular signalling. Topics discussed within this volume include lipid composition of cellular membranes and their organization in biological systems, the dynamic aspects of phospholipid ...
There is much interest today in the essentiality of choline. The proceedings of the 7th International Congress on Phospholipids updates the nutrition, health, and medical research community on the latest work being done on phospholipids in health and disease. Both review papers and original research are included.
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.