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This book is focused on a clinical-based diagnostic approach of autonomic dysfunctions, highlighting main diagnostic tools and pharmacological and non-pharmacological therapies available nowadays. The autonomic nervous system (ANS) is a subcomponent of the peripheral nervous system (PNS) and dysfunction of one or more subdivisions of the ANS, when accompanying other diseases, is linked to a worse prognosis of the latter. In some circumstances or when severe, dysfunction of ANS itself results in symptoms and disability. A myriad of factors can cause autonomic dysfunction and more than one can concur even in the same patient; due to the expansive nature of the ANS, patients can be affected by a wide range of conditions. Each chapter is characterized by a similar structure and is devoted to a different dysfunction. For each pathology, the book offers the essential information on mechanisms of action, treatments and outcomes. Written by experts in the research of these disorders, the volume addresses primarily Neurologists, but will be a useful tool also for Gastroenterologists, Ophthalmologists, Urologists, Cardiologists and Internal medicine specialists.
This comprehensive book addresses all elements of the autonomic nervous system (ANS) and sleep interaction, as well as ANS alterations in sleep and how these impact primary and comorbid sleep dysfunction. It meets the market need for a comprehensive text that deals with ANS changes in sleep and how these impact various neurological, medical, and primary sleep disorders. Organized into three parts, the book begins with a review of the foundational bodily systems that participate in coordination of ANS activity with other homeostatic responses such as respiration, cardiovascular reflexes, and responses to stress. Part two then examines methods of laboratory evaluation and the “why, when, how” of interpreting heart rate variability in sleep. To conclude, the final section of the book broadly covers the many clinical aspects of ANS, including insomnia, restless leg syndrome, sleep apnea, sleep related epilepsy, and acute autonomic neuropathy. Autonomic Nervous System and Sleep enhances the reader's understanding of the pathophysiology of various disorders, and explains how to apply this profound understanding is important to new lines of therapy to improve morbidity.
The relationship between sleep disorders – in particular sleep apnea, a highly prevalent condition – and common vascular disturbances such as stroke and hypertension is an area of active research. Summarizing the clinical evidence to date between sleep disorders and vascular pathology, this is the first time a comprehensive overview of this relationship has been covered in a single volume. Bringing together some of the world's most renowned authors in the field, Sleep, Stroke and Cardiovascular Disease contains recommended treatment plans – allowing for rapid and accurate diagnosis and management of patients – enabling learning from real experience. Of interest, not only, to specialists who intervene in diagnosis and management of sleep and stroke disorders such as neurologists, cardiologists and pulmonologists, the book will also be of value to primary-care practitioners, allowing them to arrive at better diagnoses and management of sleep and vascular disorders.
Analyzes and critiques how sleep and sleep disorders are understood and treated.
This book provides essential insights into the current state of knowledge regarding the main aspects of cluster headache and trigeminal autonomic cephalgias. The first chapters focus on classification and clinical features, together with familial and genetic aspects. Relevant animal models and the putative role of key nervous structures as the hypothalamus, brainstem, diencephalon and sphenopalatine ganglion are reviewed. Evidence gained from key molecules such as CGRP in animals and human headache models are discussed. The book subsequently presents information on the various aspects of the pathophysiology of trigeminal autonomic cephalalgias for example regarding the implication of the tri...
Sleep disorders are increasingly recognized as a major clinical problem, with significant morbidity and considerable economic importance. This compendium of case studies presents a diverse range of situations which challenge the problem-solving abilities of all those interested in sleep disorders, covering both common and unusual cases. Each case begins with a clinical history, followed by examination findings and special investigations and culminating in diagnosis, treatment and management, with discussion of differential diagnosis where appropriate. Focusing attention on the major categories of sleep medicine, including insomnia, hypersomnias, sleep-breathing disorders, parasomnias, movement disorders, circadian dysrhythmias and the neurology of sleep, this clinical guide promotes integrative thinking and diagnostic skill. Historical and review citations, illustrations and concise real-life stories stimulate memory and facilitate learning. Written and edited by an international cadre of sleep professionals, this book will inform and challenge established specialists and provide a stimulating teaching tool for those in training.
The Primer on the Autonomic Nervous System presents, in a readable and accessible format, key information about how the autonomic nervous system controls the body, particularly in response to stress. It represents the largest collection of world-wide autonomic nervous system authorities ever assembled in one book. It is especially suitable for students, scientists and physicians seeking key information about all aspects of autonomic physiology and pathology in one convenient source. Providing up-to-date knowledge about basic and clinical autonomic neuroscience in a format designed to make learning easy and fun, this book is a must-have for any neuroscientist's bookshelf! Greatly amplified and updated from previous edition including the latest developments in the field of autonomic cardiovascular regulation and neuroscience Provides key information about all aspects of autonomic physiology and pathology Discusses stress and how its effects on the body are mediated Compiles contributions by over 140 experts on the autonomic nervous system
This book offers clear, detailed guidance on all aspects of prognostic evaluation in patients who have been involved in a serious accident with neurological consequences or have been diagnosed with a severe neurological illness. It covers the full range of disorders of the central and the peripheral nervous system, not only providing very accurate prognostic estimates but also addressing relevant clinical issues, differential diagnosis, and the role of imaging. The book is practically oriented and designed for use on a daily basis when assessing prognosis and discussing the outcome with patients, their families, and other interested parties. It will support patient–doctor partnerships by ensuring that the most professional answers can be given to patients' and doctors' questions and by promoting realistic expectations of the effect of medical interventions. In addition, it will enable doctors, lawyers, and other professionals to understand relevant issues when an estimate of prognosis and life expectancy is the subject of legal dispute.
This volume is comprised of the majority of lecture presentations and a few select posters presented at the International Workshop, "Basal Ganglia and Thalamus in Health and Movement Disorders," held in Moscow, Russia, on May 29-31, 2000. The International Committee responsible for organizing this workshop included Alexander Konovalov, Director, Burdenko Institute of Neurosurgery of the Russian Academy of Medical Sciences, Mahlon DeLong, Chair, Department of Neurology, Emory University, Atlanta, USA, Alim Louis Benabid, Chief, Neurosurgery Service, University of Joseph Fourrier, Grenoble, France, and the two undersigned. The workshop was conceived out of a desire to provide a forum for discussions of both basal ganglia-and motor thalamus-related issues by bringing together basic scientists and clinicians representing different disciplines, research directions, and philosophies. The primary goals were to encourage an exchange of information and ideas in an informal environment, to stimulate integration of the data from different disciplines, and to identifY controversial issues and the most essential questions to be addressed in future research.
This new edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, and continues to provide practitioners from a variety of fields with a rational guide to aid in the recognition and management of autonomic disorders.