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Anti-Prostate Cancer Agents walks the readers through the anti-prostate cancer drug development pipeline from early discovery/design to clinical studies/applications. This book covers discovery/design, synthetic studies, preclinical evaluation, mechanism of action, structure-activity relationships, clinical studies/applications of anti-prostate cancer agents. This book provides insight on how the design and discovery process of anti-prostate cancer agents have evolved from androgen deprivation therapy to current androgen receptor antagonists/degraders. So far, no book focusing on the topic has been published.
This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than 40 years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. - Comprehensive, up-to-date reviews - Contributions from leading authors in their respective fields - Broad coverage of the chemical and biological aspects of important natural products
"Seventh Prince, do you see the smoky makeup I drew for you today?""Hongliang, Miss Qiao has an eyesight ailment. Take her back to the residence. I request that you accompany me to treat Miss Qiao.""Hey, Seventh Prince, don't go away yet. There's nothing wrong with my eyes, and I haven't slept for the whole night. I wrote a few poems for you, you can listen to them.""The seventh prince is the sky, the seventh prince is the earth, and the seventh prince is the radish and vegetables." Small cool is a flower, small cool is a treasure, small cool is that day fairy. "Ah — the flower and the radish with the fairy, a natural pair!"Just as she finished speaking, the purple-clothed servant girl stood beside the pink-clothed lady with big strides and also held up the cloth in her hand. She recited: "You are the number one marshal in the world, I am the prettiest in the world, you and I love each other and have a fat child to kiss!"
"Seventh Prince, have you seen how well I've painted your smoky makeup today?" "Hong Liang, Miss Qiao has a sharp eye. She is to be escorted back to the mansion and is to be accompanied by Su Erzhong to treat Miss Qiao." "Hey, Seventh Prince, don't go yet. There's nothing wrong with my eyes, and I haven't slept for the whole night. I've written a few poems for you, you can listen to them." Seventh Prince was the heavens, Seventh Prince was the earth, and Seventh Prince was the radish and vegetables. Small cool is a flower, small cool is a treasure, small cool is that day fairy. "Ah — the flower and the radish with the fairy, a natural pair!" Just as she finished speaking, the purple-clothed servant girl stood beside the pink-clothed lady with big strides and also held up the cloth in her hand. She recited: "You are the number one marshal in the world, I am the prettiest in the world, you and I love each other and have a fat child to kiss!"
Fruits and vegetables are an important part of a healthy diet. However, one third of fruit and vegetables are lost after harvest every year. Most losses are caused by pathogen (mostly fungi) infections, which lead to postharvest decay. In addition, some postharvest fungal pathogens can produce toxic secondary metabolites (i.e. mycotoxins) during their infecting periods. Mycotoxin contamination may cause serious food safety issues. At present, the use of synthetic fungicides is still the main means to control postharvest diseases. However, the development of resistance in fungal pathogens to fungicides and the growing public concern over the health and environmental risks associated with high levels of pesticides in fruits and vegetables have urged researchers to develop alternative methods of disease control. A deeper understanding of the infecting mechanisms of postharvest pathogens will provide great insight into developing new controlling strategies.
Mercenary King Chen Yang returned to the city to protect his comrade's sister, the goddess. In the bustling city, Chen Yang was like a fish in water, carefree and at ease. And to see how the previous generation's soldiers would use their iron fists and wits to build a business empire...
This book presents the proceedings of the International Conference on Intelligent, Interactive Systems and Applications (IISA2018), held in Hong Kong, China on June 29–30, 2018. It consists of contributions from diverse areas of intelligent interactive systems (IIS), such as: autonomous systems; pattern recognition and vision systems; e-enabled systems; mobile computing and intelligent networking; Internet & cloud computing; intelligent systems and applications. The book covers the latest ideas and innovations from both the industrial and academic worlds, and shares the best practices in the fields of computer science, communication engineering and latest applications of IOT and its use in industry. It also discusses key research outputs, providing readers with a wealth of new ideas and food for thought.