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Drug Discovery
Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contribut...
Novel Carbon Adsorbents
Following in the lineage of Adsorption by Carbons (Bottani & Tascon, 2008), this work explores current research within contemporary novel carbon adsorbents. Both basic and applied aspects are discussed for this important class of materials. The first section of the book introduces physical adsorption and carbonaceous materials, and is followed by a section concerning the fundamentals of adsorption by carbons. This leads to development of a series of theoretical concepts that serve as an introduction to the following section in which adsorption is mainly envisaged as a tool to characterize the porous texture and surface chemistry of carbons. Particular attention is paid to novel nanocarbons, ...
Preparation of Solid Catalysts
Solid catalysts play a fundamental role in all areas between basic research and industrial applications. This book offers a large amount of information about the preparation of solid catalysts. All types of solid catalysts and all important aspects of their preparation are discussed. The highly topical contributions are written by leading experts in disciplines ranging from solid state, interface and solution chemistry to industrial engineering. The straightforward presentation of the material and the comprehensive coverage make this book an essential and indispensible tool for every scientist and engineer working with solid catalysts.
Repetitive Structures in Biological Sequences: Algorithms and Applications
Repetitive structures in biological sequences are emerging as an active focus of research and the unifying concept of "repeatome" (the ensemble of knowledge associated with repeating structures in genomic/proteomic sequences) has been recently proposed in order to highlight several converging trends. One main trend is the ongoing discovery that genomic repetitions are linked to many biological significant events and functions. Diseases (e.g. Huntington's disease) have been causally linked with abnormal expansion of certain repeating sequences in the human genome. Deletions or multiple copy duplications of genes (Copy Number Variations) are important in the aetiology of cancer, Alzheimer, and...
Wind Turbine Technology
This title includes a number of Open Access chapters. This important book presents a selection of new research on wind turbine technology, including aerodynamics, generators and gear systems, towers and foundations, control systems, and environmental issues. This informative book: • Introduces the principles of wind turbine design • Presents methods for analysis of wind turbine performance • Discusses approaches for wind turbine improvement and optimization • Covers fault detection in wind turbines • Describes mediating the adverse effects of wind turbine use and installation
Engineering Design and Mathematical Modelling
Engineering Design and Mathematical Modelling: Concepts and Applications consists of chapters that span the Engineering design and mathematical modelling domains. Engineering design and mathematical modelling are key tools/techniques in the Science, Technology and Innovation spheres. Whilst engineering design is concerned with the creation of functional innovative products and processes, mathematical modelling seeks to utilize mathematical principles and concepts to describe and control real world phenomena. Both of these can be useful tools for spurring and hastening progress in developing countries. They are also areas where Africa needs to ‘skill-up’ in order to build a technological base. The chapters in this book cover the relevant research trends in the fields of both engineering design and mathematical modelling. This book was originally published as a special issue of the African Journal of Science, Technology, Innovation and Development.
Endocrine Oncology
Stephen P. Ethier and a panel of leading investigators comprehensively analyze the cellular, molecular, and endocrine factors in the development of cancers of the breast, prostate, endometrium, and ovary. Concentrating on defining the most important unresolved issues in the field, the authors review how steroid hormones function to regulate normal mammary gland homeostasis in humans, with particular emphasis on the roles of estrogen, progesterone, and growth factors. Comprehensive and up-to-date, Endocrine Oncology offers both basic and clinical researchers not only the latest molecular and cellular findings on endocrine cancers, but also a powerful critical analysis that will prove invaluable to all endocrinologists and oncologists working in the area today.
Carbons for Electrochemical Energy Storage and Conversion Systems
As carbons are widely used in energy storage and conversion systems, there is a rapidly growing need for an updated book that describes their physical, chemical, and electrochemical properties. Edited by those responsible for initiating the most progressive conference on Carbon for Energy Storage and Environment Protection (CESEP), this book undoub
Advanced Control & Optimization Paradigms for Energy System Operation and Management
Distributed energy technologies are gaining popularity nowadays; however, due to the highly intermittent characteristics of distributed energy resources, a larger penetration of these resources into the distribution grid network becomes of major concern. The main issue is to cope with the intermittent nature of the renewable sources alongside the requirements for power quality and system stability. Unlike traditional power systems, the control and optimization of complex energy systems comprising of wind, solar, thermal, and energy storage becomes difficult in many aspects, such as modelling, integration, operation, coordination and planning etc. This means that energy conversion as per the ...
