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Aphasia in Atypical Populations
Theory and research in aphasiology have typically concentrated on a limited population--right-handed adult monolinguals whose language uses an alphabetic code. Bilingual individuals, ideographical code users, and children (among others) have been separated out. This book examines the available data from these "atypical" aphasics, asking whether what makes them different has a significant effect on language representation and processing in the brain. Each chapter reviews literature pertinent to a given population and explores whether (and potentially how) these populations differ from the "typical" aphasic population. The ultimate goal is to better understand whether the model of language used in aphasiology can be extended to these "atypical" populations, or conversely, whether significant differences merit the development of a new model.
Acquired Aphasia
With chapters containing up to 50 percent new coverage, this book provides a thorough update of the latest research and development in the area of acquired aphasia. Coverage includes the symptoms of aphasia, assessment, neuropsychology, the specific linguistic deficits associated with aphasia, related disorders, recovery, and rehabilitation. This comprehensive compilation, written by some of the most knowledgeable workers in the field, provides an authoritative text and reference for graduate students, clinicians, and researchers. - Chapters include up to 50 percent new coverage - Provides update of latest research in the field - Includes writings by the most knowledgeable workers in the field - Comprehensive, exhaustive reference tool
Peptide-based Drug Discovery
With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies. What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What are emerging therapeutics for peptide modalities? This book answers these questions with a holistic story from molecules to medicine, combining the themes of design, synthesis and clinical applications of peptide-based therapeutics and biomarkers. Chapters are written and edited by leaders in the fie...
Current Concepts in Carnitine Research
Current Concepts in Carnitine Research is based on the proceedings of a symposium on carnitine research presented by the School of Medicine, Medical College of Georgia, April 20-21, 1991. The book is intended to introduce areas of carnitine research and explore key clinical and basic aspects of carnitine metabolism. The four major topics covered are carnitine and the heart; the structure, function, and regulation of carnitine palmitoyl transferase; functions of the short chain carnitine acyltransferase; and areas of carnitine research. This information is essential for physicians and biochemists studying intermediate metabolism, nutritionists involved in dietary nanuplication, and cardiology researchers, especially those studying cardiomyopathy.
Handbook of Neurolinguistics
The Handbook of Neurolinguistics is a state-of-the-art reference and resource book; it describes current research and theory in the many subfields of neurolinguistics and its clinical application. Thorough and clearly written, the handbook provides an excellent overview of the field of neurolinguistics and its development. The book is organized into five parts covering the history of neurolinguistics, methods in clinical and experimental neurolinguistics, experimental neurolinguistics, clinical neurolinguistics, and resources in neurolinguistics. The first four parts contain a wide range of topics which discuss all important aspects of the many subfields of neurolinguistics. Also included ar...
The Tai-Kadai Languages
The Routledge Language Family Series is aimed at undergraduates and postgraduates of linguistics and language, or those with an interest in historical linguistics, linguistics anthropology and language development. With close to 100 million speakers, Tai-Kadai constitutes one of the world's major language families. The Tai-Kadai Languages provides a unique, comprehensive, single-volume tome covering much needed grammatical descriptions in the area. It presents an important overview of Thai that includes extensive cross-referencing to other sections of the volume and sign-posting to sources in the bibliography. The volume also includes much new material on Lao and other Tai-Kadai languages, s...
South and Southeast Asian Psycholinguistics
This groundbreaking volume explores the languages of South and Southeast Asia, which differ significantly from Indo-European languages in their grammar, lexicon and spoken forms. This book raises new questions in psycholinguistics and enables readers to re-evaluate previous models in light of new research.
Metallobiolomics
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Evolution of Extracellular Matrix
The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.
