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The Mitoribosome
This volume provides classic and new methods to study the structure, assembly pathway, and protein synthesis ability of mitoribosomes across species. Following an introduction of fundamental concepts on the topic, method chapters present detailed protocols based on cryo-electron tomography, cryo-EM approaches, mitoribosome purification techniques, mitochondrial translation assays, and methods to study mitochondrial mRNAs that are translated on mitoribosomes. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, The Mitoribosome: Methods and Protocols, aims to be a comprehensive guide for researchers in the field.
Water Conservation, Recycling and Reuse: Issues and Challenges
Water - a basic element of life, livelihood, food security and sustainable development - holds the key to global sustainability. The global water demand has been increased 3-fold in the past five decades and only 0.4% of the total world’s fresh water resources is available and accessible for use. The United Nations projected that half of all countries will face water scarcity by 2025 and more than one-third of the world’s population could be affected by water stress by 2050. The water problem is rapidly intensifying in the Asian region, and around 700 million people do not have access to safe drinking water. Similarly, according to the Intergovernmental Panel on Climate Change (IPCC) rep...
RNA - Ligand Interactions, Part A: Structural Biology Methods
RNA-Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X-ray crystallography, NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology, focuses on molecular biology methods.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the Series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Emerging Trends in Chemical Sciences
Thirty carefully selected, peer-reviewed contributions from the International Conference on Pure and Applied Chemistry (ICPAC 2016) are featured in this edited book of proceedings. ICPAC 2016, a biennial meeting, was held in Mauritius in July 2016. The chapters in this book reflect a wide range of fundamental and applied research in the chemical sciences and interdisciplinary subjects. This is a unique collection of full research papers as well as reviews.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Environmental Contaminants
This new volume looks at the impact, assessment, and remediation of various environmental contaminants. It discusses the environmental changes that can occur due to arsenic, heavy metals, herbicides, fluorides, microplastics, chemical fertilizers contaminants; the remedial measures of these environmental contaminants; and how to analyze trace-level concentrations of contaminants.
Public Health and Toxicology Issues in Drug Research, Volume 2
Toxicodynamics in Drug Research, Volume 2: Public Health and Toxicology Issues examines the implications of public health issues and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments on human health. Volume 2: Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics covers topics on pharmacokinetics and toxicokinetics such as population pharmacokinetics/toxicokinetics, the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. The book investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-in...
