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This book summarizes the current state of movement disorder management and the role of surgical therapies as an alternative to medication. Following a chapter on the history of movement disorder surgery, leaders in their fields describe the pathophysiology, functional neuroanatomy, clinical presentation, and medical management of Parkinson’s disease, dystonia, and essential tremor. This is followed by chapters on the spectrum of movement disorder surgery itself, from the lesioning procedures of radiofrequency ablation, stereotactic radiosurgery, and high-frequency ultrasound to the modulatory procedures of “asleep”, image-guided deep brain stimulation (DBS) and “awake”, microelectrode-guided DBS. The final chapters focus on closed-loop DBS, drug-delivery, gene therapy, and other emerging neurosurgical therapies, highlighting long-standing experimental strategies that are reaching exciting phases of clinical translation. This volume is a valuable tool for accessing the wide spectrum of concepts that currently define this dynamic field.
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How has our understanding of our world and our place in the universe changed in recent decades through the momentous discoveries of science? Do recent developments in the philosophy of science, which place limitations on scientific knowing, provide a more level playing field? This collection of essays and sermons, which have not been readily available before, address these thought-provoking questions. The John Templeton Foundation sponsored an essay and sermon contest to convey an expanded vision of God, one that is informed by recent discoveries of science on the nature of the universe and the place we have in the world. These selections are the winners of that competition. The book is divi...
Neuro-oncologic (brain and spine) cancers account for 19,000 new cases and 13,000 deaths per year. The early and proper diagnosis of these virulent cancers is critical to patient outcomes and diagnosis and treatment strategies are continually evolving. The multidisciplinary team that manages these patients involves medical and radiation oncology, neurosurgery, neuroimaging, nurses and therapists. Principles and Practices of Neuro-Oncology establishes a new gold standard in care through a comprehensive, multidisciplinary text covering all aspects of neuro-oncology. Six major sections cover all topics related to epidemiology and etiology, molecular biology, clinical features and supportive car...
Robert Frost was a practicing farmer, a skilled naturalist and one of America's best-loved poets. His body of work provides a vivid and compelling narrative of New England's changing environment--though it can be hard to discern when its parts are scattered through hundreds of different poems, voices and moods. This book pieces together Frost's environmental commentary, examining his poems thematically and in a logical order. In them, homesteads are carved out of the forest, families make their living from an obdurate land, property is abandoned when it fails to sell, and plants and animals reclaim deserted farms. Frost bemoaned the loss of people from the land but also celebrated the flora and fauna that thrived in fallow fields and empty barns.
In this issue of Neurosurgery Clinics, guest editors Drs. Robert J. Dempsey and Michael M. Haglund bring their considerable expertise to the topic of Global Neurosurgery. Top experts in the field cover the delivery of neurosurgical care in a variety of settings, discussing topics such as worldwide need and disparities; medical curriculum development for a worldwide curriculum for neurosurgery; continuing medical education for graduates; key partners in global health; bioengineering in global health; and much more. - Contains 16 relevant, practice-oriented topics including overview on global neurosurgery; global neurosurgery and international policy; establishing microsurgical skills laborato...