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Molecular Genetics of Inherited Eye Disorders
Molecular Genetics of Inherited Eye Disorders provides an authoritative and up-to-date account of molecular genetic advances in a wide spectrum of genetic eye disorders, and forms the second volume in the Modern Genetics book series. The field has produced some dramatic and often unexpected findings in recent years ranging from the elegant unravelling of the molecular basis of colour vision defects to the subtle complexity of the retinoblastoma gene. The role of crystallins in congenital cataract and of the rhodopsin molecule in retinitis pigmentosa are discussed, illustrating the importance of the candidate gene approach to genetic eye disease. Reverse genetic approaches to the cloning of genes responsible for aniridia and choroideremia exemplify the power of the new genetic techniques and signal the start of the next experimental phase, in which the functional characterization of identified genes begins.
Essentials of Bioinformatics, Volume I
Bioinformatics is an integrative field of computer science, genetics, genomics, proteomics, and statistics, which has undoubtedly revolutionized the study of biology and medicine in past decades. It mainly assists in modeling, predicting and interpreting large multidimensional biological data by utilizing advanced computational methods. Despite its enormous potential, bioinformatics is not widely integrated into the academic curriculum as most life science students and researchers are still not equipped with the necessary knowledge to take advantage of this powerful tool. Hence, the primary purpose of our book is to supplement this unmet need by providing an easily accessible platform for st...
Plant Mitochondria
This book is a printed edition of the Special Issue "Plant Mitochondria" that was published in IJMS
Reasoning Web
This book contains a collection of thoroughly revised tutorial papers based on lectures given by leading researchers at the 4th International Summer School on the Reasoning Web, held in Venice, Italy, in September 2008. The objective of the book is to provide a coherent introduction to semantic web methods and research issues with a particular focus on reasoning. The seven tutorial papers presented provide competent coverage of methods and major application areas such as social networks, semantic multimedia indexing and retrieval, bioinformatics, and semantic web services. They highlight which techniques are already being successfully applied for purposes such as improving the performance of information retrieval algorithms, enabling the interoperation of heterogeneous agents, modelling users profiles and social relations, and standardizing and improving the accuracy of very large and dynamic scientific databases.
Thioredoxin and Glutaredoxin Systems
This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the ...
Canada Lancet
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