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Re-irradiation: New Frontiers
New developments such as refined combined modality approaches and significant technical advances in radiation treatment planning and delivery are facilitating the re-irradiation of previously exposed volumes. As a consequence, both palliative and curative approaches can be pursued at various disease sites. Re-irradiation: New Frontiers is the first book to provide a comprehensive overview on current re-irradiation strategies. Re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance are all discussed in detail. In addition, disease-specific chapters document recent clinical results and future research directions. Professionals involved in radiation treatment planning and multimodal oncology treatment will find this book to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.
Myosins
This highly authoritative volume highlights the remarkable superfamily of molecular motors called myosins, which are involved in such diverse cellular functions as muscle contraction, intracellular transport, cell migration and cell division. In a timely compilation of chapters written by leading research groups that have made key discoveries in the field, the current understanding of the molecular mechanisms and biological functions of these intriguing proteins is explored.
Proceedings
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Treatise on Geochemistry
This extensively updated new edition of the widely acclaimed Treatise on Geochemistry has increased its coverage beyond the wide range of geochemical subject areas in the first edition, with five new volumes which include: the history of the atmosphere, geochemistry of mineral deposits, archaeology and anthropology, organic geochemistry and analytical geochemistry. In addition, the original Volume 1 on "Meteorites, Comets, and Planets" was expanded into two separate volumes dealing with meteorites and planets, respectively. These additions increased the number of volumes in the Treatise from 9 to 15 with the index/appendices volume remaining as the last volume (Volume 16). Each of the origin...
Cardiac Energetics
Assessment of cardiac energetics at the level of ATP-synthesis, chemomechanical energy transformation and whole organ dynamics as a function of haemodynamic load, ventricular configuration and oxygen- and substrates supply is basic to understanding cardiac function under physiological and pathophysiological (hypertrophy, hypoxia, ischaemia and heart failure) conditions. Moreover, cardiac energetics should be an important consideration in the choice and application of drugs especially in the case of vasodilators, inotropic agents and in cardioprotective measures. Only by considering energetics at the subcellular, cellular, and whole-heart level we can arrive at a better understanding of cardi...
Mammalian Transient Receptor Potential (TRP) Cation Channels
In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
IFYGL Bulletin
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Creatine and Creatine Kinase in Health and Disease
This volume places emphasis on the intricate interplay between creatine and creatine kinase function on one hand and proper brain function, neurodegenerative disease and/or neuroprotection on the other. The book, compiled by outstanding experts, provides a key reference summarizing the state-of-the-art in creatine and creatine kinase research. It is a must-read for understanding the links between creatine metabolism and neuroprotection as well as neurodegenerative disease.
