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Despite intense political focus and debate for the past 10 years, Americans remain deeply worried about the availability and affordability of health care for themselves and their families. In clear and accessible prose, journalist Ryan Holeywell and medical doctor and health policy expert Arthur Garson provide Americans with the tools we need to have an honest, unbiased view of the state of health care policy in America. By fact checking 20 enduring health care myths they move the debate beyond Obamacare v. repeal and replace and give citizens the tools they need to evaluate the major policy issues confronting our health care system.
This volume details comprehensive protocols and methodologies to assess mitochondrial bioenergetics and dynamics in different tissues and cells involving health and pathological states. Chapters guide readers through methods for assessment of the energy metabolism including Oxygen Consumption Rate (OCR), mitochondrial membrane potential, and measuring mitochondrial Ca2+ handling, and ROS emission. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting, and systematic reproducible protocols. Authoritative and cutting-edge, Mitochondria: Methods and Protocols aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.
Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases. To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine. With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.
The Frontiers in Materials Editorial Office team are delighted to present the inaugural “Frontiers in Materials: Rising Stars” article collection, showcasing the high-quality work of internationally recognized researchers in the early stages of their independent careers. All Rising Star researchers featured within this collection were individually nominated by the Journal’s Chief Editors in recognition of their potential to influence the future directions in their respective fields. The work presented here highlights the diversity of research performed across the entire breadth of the materials science and engineering field, and presents advances in theory, experiment and methodology w...
Examines risks to mental health for people facing emergencies, incidents, disasters, and pandemics and how to meet their needs.
The contributors to this volume include many of the distinguished researchers in this area. Many of these scholars have collaborated with Joseph McKean to develop underlying theory for these methods, obtain small sample corrections, and develop efficient algorithms for their computation. The papers cover the scope of the area, including robust nonparametric rank-based procedures through Bayesian and big data rank-based analyses. Areas of application include biostatistics and spatial areas. Over the last 30 years, robust rank-based and nonparametric methods have developed considerably. These procedures generalize traditional Wilcoxon-type methods for one- and two-sample location problems. Res...
Geospatial technology is a combination of state-of-the-art remote sensing and technology for geographic information systems (GIS) and global navigation satellite systems (GNSS) for the mapping and monitoring of landscapes and environment. The main thrust of using geospatial technology is to understand the causes, mechanisms, and consequences of spatial heterogeneity, while its ultimate objective is to provide a scientific basis for developing and maintaining ecologically, economically, and socially sustainable landscapes. This book presents new research on the interdisciplinary applications of geospatial technology for identification, assessment, monitoring, and modelling issues related to l...
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Understanding the Basics of Nanoindentation and Why It Is ImportantContact damage induced brittle fracture is a common problem in the field of brittle solids. In the case of both glass and ceramics-and as it relates to both natural and artificial bio-materials-it has triggered the need for improved fabrication technology and new product development