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Introduces a range of data analysis problems encountered in drug development and illustrates them using case studies from actual pre-clinical experiments and clinical studies. Includes a discussion of methodological issues, practical advice from subject matter experts, and review of relevant regulatory guidelines.
The pace of therapeutic advances in the treatment of cardiovascular diseases is rapid, and new clinically-relevant information appears with such frequency that it can be extremely challenging for clinicians to keep up. Still, knowledge and interpretation of major clinical trials is crucial for the range of clinicians who manage cardiovascular patients, especially since important trial evidence often needs to be implemented soon after it is published. Confidently apply gold standard treatment for 10 of the most critical areas of cardiology Written by an international team of experts, Cardiovascular Clinical Trials: Putting the Evidence into Practice: Provides a succinct overview of recent maj...
Originally published in 1986, this volume presents the clinical and administrative aspects of emergency psychiatry from the point of view of the clinician administrator involved in organizing and running an emergency service. Part 1 provides an administrative overview of psychiatric emergency care – the development of the field, the concepts, the patient profile, the team, the architecture, fiscal planning, legal constraints as well as training and research issues. Part 2 describes psychiatric emergency care delivery systems in the emergency department, the average hospital wards, the community mental health centers and health maintenance organizations. Part 3 gives examples of the process...
The latest assessment techniques for all professionals in emergency psychiatry.
This book offers extensive and valuable advice for researchers starting with pharmaceutical studies and doctoral dissertation writing. The contributors provide precise, detailed instructions covering every phase of the research process, from choosing a topic to sharing findings, because they know the intricacies and difficulties that come with it. Essential topics covered in the book include writing a professional thesis, conducting literature reviews, planning experimental methods, and guaranteeing ethical human and animal research procedures. The book promises to provide researchers with the information and abilities required to succeed academically and professionally in the pharmaceutical...
Mathematical Modeling demonstrates the usefulness of mathematical modeling as applied to emergency health services settings. It is written for those involved in the daily activities of emergency health systems as well as for researchers and mathematicians/statisticians.
Biosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in clinical development, this book discusses various potential drug development strategies, the design and analysis of pharmacokinetics (PK) studies, and the design and analysis of efficacy studies.
Essential Cardiology: Principles and Practice, 3rd Edition, blends molecular, cellular, and physiologic concepts with current clinical practice and provides up-to-date information on all major aspects of cardiovascular disease. Fully revised by an international panel of leading authorities in the field, it is an authoritative resource for cardiologists, internists, residents, and students. The book presents the clinical examination of the patient, including diagnostic testing and cutting-edge radiologic imaging; pathogenesis and treatment of various types of cardiac abnormalities; the needs of special populations, including pregnant, elderly, and renal-compromised patients; cardiovascular gene and cell therapy; and preventive cardiology. It includes new chapters on cardiovascular disease in women; diabetes and the cardiovascular system; and cancer therapy-induced cardiomyopathy. The Third Edition also focuses on the substantial advances in anti-platelet and anticoagulant therapy; new modalities of cardiac imaging; new anti-arrhythmic drugs; and a sophisticated understanding of vascular biology and atherogenesis.
An all-inclusive overview of cardiology in a trusted landmark reference A Doody's Core Title ESSENTIAL PURCHASE! 5 STAR DOODY'S REVIEW! "This well-organized textbook begins with a thoughtful discussion of cardiology's past and future. It presents readers with the foundations of cardiovascular medicine and the basics of cardiovascular evaluation. These initial chapters provide an excellent overview of topics in general cardiology from guidelines to newer diagnostic modalities such as MRI, CT, and PET. Subsequently, the book is organized to provide readers with a focused approach to other areas of cardiology from heart failure to electrophysiology and interventional cardiology." This is a very...