Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
HIV I: Molecular Biology and Pathogenesis: Clinical Applications
The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, ...
Regulators and Effectors of Small GTPases: Ras Family
The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continually increasing, functionally complex array of downstream effectors. Since the last Methods in Enzymo...
Drug-Drug Interactions: Scientific and Regulatory Perspectives
DrugDrug Interactions is a comprehensive review of the scientific and regulatory perspectives of drugdrug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drugdrug interactions, the prediction of drugdrug interaction potential of new drugs, and the avoidance of clinically significant drugdrug interaction in patients. - Provides useful references on the science of drug-drug interactions - Describes in a basic and comprehensive manner drug-drug interactions from the mechanistic viewpoint - Contains original data from academic and industrial laboratories - Presents an overview of regulatory agency positions
Hormones and Signaling
Hormones and Signaling focuses on the mechanisms of gene regulation at the cellular level. It also describes the actions of hormones in modulating gene regulation and animal development. - Glococorticoid and mineralcorticoid signaling - Orphan nuclear receptors - Nuclear receptor coactivators - Cytokines and STAT signaling - Coordination of cAMP signaling events through PKA anchoring - G protein-coupled extracellular Ca2+ (Ca2+0)-sensing receptor (CaR) - Pancreatic islet development - Genetic analysis of androgen receptors in development and disease - Antioprogestin regulable gene switch for induction of gene expression in vivo - Steroid receptor knockout model
HIV: Molecular Biology and Pathogenesis: Viral Mechanisms
The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, ...
Catecholamines: Bridging Basic Science with Clinical Medicine
This volume in Advances in Pharmacology focuses on all aspects of catecholamine research, from very basic to medical. It is broad based and covers many areas within physiology and medicine.
Roles of Vasopressin and Oxytocin in Memory Processing
The Roles of Vasopressin and Oxytocin in Memory Processing reviews research progress in a subfield of Behavioral Pharmacology concerned with vasopressin's (VP's) and oxytocin (OT's) roles in memory processing (MP). As hormones, VP is well-known for its pressor and antidiuretic action, and OT for its contribution to parturition and nursing. As neurotransmitters, they participate in a wide variety of self- and species-preserving functions expressed at psychological, physiological and behavioral levels. Advances in Pharmacology is available online on ScienceDirect — full-text online of volumes 48 onwards. Elsevier book series on ScienceDirect gives multiple users throughout an institution sim...
Cancer Chemoprevention
Accompanying CD-ROM in pocket at end of v. 2 contains a compact e-book version of v. 2.
