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The grammar of focus has been studied in generative grammar from its inception. It has been the subject of intense, detailed cross-linguistic investigation for over 20 years, particularly within the Principles and Parameters framework. It is appropriate at this point, therefore, to take stock. Appraisal at this particular point is all the more legitimate because it comes at a time of general evaluation of the results of the profound activity that has characterized the Principles and Parameters framework. This general assessment has produced a radical new direction within that framework. The volume starts off with an introductory chapter that aims to provide an outline for the assessment, to be followed by an overview of the evolution of the study of focus in generative grammar, and a recapitulation of the principal issues associated with focus. These issues are taken up in the remaining chapters of the book, where various grammatical means of marking focus (as well as grammaticalization of focus marking) are analyzed in a wide variety of languages.
Postwertzeichen, Briefmarke, Frankomarke ; International ; Philatelie.
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The most recent developments in diagnostic and therapeutic aspects of Gliomas (Glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers is included. The identification and validation of brain cancer (glioblastoma) genes are discussed. Role of cancer stem cells in the initiation, progression, and persistence of malignant gliomas is explained. The use of surgical resection, chemotherapy (e.g., temozolomide), immunotherapy, and radiotherapy for malignant glioblastoma are pointed out. Standard (established) as well as newer imaging modalities (proton magnetic resonance spectroscopy) are discussed.