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Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases
This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg), mesenchymal stromal/stem cells, and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations; and the advantages and disadvantages of HSCT in the treatment of a variety of autoimmune d...
The EBMT Handbook
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Hematopoietic Stem Cell Transplantation for Neurologic Diseases
Intense immunosuppression followed by Hematopoietic Stem Cell Transplantation for Neurological Diseases (HSCT) has been evaluated as a possible therapeutic tool in severe autoimmune diseases for the last 20 years. In the neurological field, HSCT has been widely investigated for the treatment of multiple sclerosis and evidence is accumulating about its potential use in neuromyelitis optica, stiff person syndrome, myasthenia gravis and many immune neuropathies. This volume summarizes that research. Besides their strong clinical relevance, studies on HSCT in neurological diseases have contributed to mew insights on the pathological mechanisms underlying CNS autoimmunity. - Reviews immunological mechanisms of HSCT and CNS autoimmunity - Identifies neurological diseases showing treatment efficacy with HSCT - Includes MS, myasthenia gravis, neuromyelitis optica, and more - Covers early and late side effects of HSCT
Trends in Stem Cell Biology and Technology
The study of stem cell research has recently gained the attention from a growing, multidisciplinary community of scientist; this exponential growth of interest is driven by the hope of discovering cures for several diseases through transplantation medicine. Trends in Stem Cells Biology and Technology aptly serves this developing community as it reveals new aspects of stem cell research by specifically covering studies focused on spermatogonial stem cells, uniparental embryonic stem cell lines, the generation of gametes from stem cells, reprogramming germ cells to stem cells, nuclear and somatic cell genetic reprogramming, tissue engineering and mechanotransduction of stem cells and finally the development of stem cell technologies for the treatment of deafness, heart disease, corneal injury and diabetes. With contributions by leading scientists and renowned scholars, Trends in Stem Cells Biology and Technology offers a wide audience cutting edge information at a crucial time in this ever expanding field.
The Proceedings of the 20th Anniversary History of Medicine Days Conference 2011
This volume is the third in a peer-reviewed series of Proceedings Volumes from the Calgary History of Medicine Days conferences, produced by Cambridge Scholars Publishing. The History of Medicine Days is a two day, national conference held annually at the University of Calgary, Canada, where undergraduate and early graduate students from across Canada, the US, UK, and Europe give paper and poster presentations on a variety of topics from the history of medicine and health care. The selected 2011 conference papers assembled in this volume particularly comprise insights into the histories of Wome.
EBMT HANDBOOK
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